Search for dissertations about: "gene interaction"

Showing result 1 - 5 of 779 swedish dissertations containing the words gene interaction.

2. 1. Coffee and gene interaction. The effect on methionine and lipid metabolism

   Author : Elisabeth Strandhagen; Göteborgs universitet; []
   Keywords : coffee; homocysteine; cholesterol; folate; pyridoxine; MTHFR; APOE; gene; polymorphism; interaction;

   Abstract : Background: Different dietary factors influence the risk of coronary heart disease (CHD), most likely in an interaction with genetic polymorphisms. The knowledge about such interactions is insufficient. Some observational studies have shown an association between coffee and CHD, others have not. Coffee consumption affects some CHD risk factors, e. READ MORE

4. 2. Depression and Antisocial Behaviour in Adolescents : Influence of Social Status, Shaming, and Gene-Environment Interaction

   Author : Cecilia Åslund; Kent W Nilsson; Jerzy Leppert; Bengt Starrin; Lars Oreland; Lil Träskman-Bendz; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescent; antisocial behaviour; depression; gene-environment interaction; maltreatment; monoamine oxidase; serotonin; shame; social status; Child and adolescent psychiatry; Barn- och ungdomspsykiatri; barn- och ungdomspsykiatri; Child and Youth Psychiatry;

   Abstract : This thesis investigated (1) social status and shaming experiences in relation to aggressive behaviour and depression, and (2) gene-environment interactions between two genetic polymorphisms related to the serotonergic system – MAOA-VNTR and 5HTTLPR – and experiences of maltreatment in relation to delinquent behaviour and depression among adolescents. The four included studies are based on questionnaire data from the Survey of Adolescent Life in Vestmanland 2006 (SALVe-2006). READ MORE

5. 3. Genomic profiling and gene-gene interaction in rheumatoid arthritis

   Author : Klementy Shchetynsky; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Complex disease is characterized by the interplay of multiple genetic and environmental factors. Rheumatoid arthritis (RA) is a complex autoimmune disease with a pronounced genetic component, mainly due to HLA-DRB1 gene, but also a multitude of loci outside the HLA region. READ MORE

6. 4. Learning time-varying interaction networks

   Author : Vinay Jethava; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; probabilistic graphical models; gene microarray expressions; dynamic interactome; time-varying interaction networks;

   Abstract : Most biological systems consist of several subcomponents whichinteract with each other. These interactions govern the overall behaviourof the system; and in turn vary over time and in response to internaland external stress during the course of an experiment. READ MORE

7. 5. The Multifunctional HnRNP A1 Protein in the Regulation of the Cyp2a5 Gene : Connecting Transcriptional and Posttranscriptional Processes

   Author : Tina Glisovic; Matti Lang; Francoise Raffalli-Mathieu; Lorenz Poellinger; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; Cyp2a5; DNA-protein interaction; gene regulation; hnRNP A1; nucleocytoplasmic shuttling; RNA-protein interaction; RNA stabilization; posttranscriptional; transcriptional; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi;

   Abstract : The mouse xenobiotic-inducible Cyp2a5 gene is both transcriptionally and posttranscriptionally regulated. One of the most potent Cyp2a5 inducers, the hepatotoxin pyrazole, increases the CYP2A5 mRNA half-life. READ MORE