Search for dissertations about: "glial cultures"
Showing result 1 - 5 of 78 swedish dissertations containing the words glial cultures.
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1. Neuronal and glial differentiation of expanded neural stem and progenitor cells; in vitro and after transplantation
Abstract : In this thesis we have used cells dissected from the lateral ganglionic eminence (LGE), the medial ganglionic eminence (MGE), and the cortical primordium of the embryonic mouse forebrain. The tissue was dissected from either i) wild-type mice, ii) green fluorescent protein (GFP)-, or iii) Gtv-a-expressing transgenic mice, and subsequently grown and expanded in vitro using two different protocols. READ MORE
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2. Glycosaminoglycans in cultures of normal and malignant glial cells
Abstract : .... READ MORE
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3. Ion Transport in Glial and Neuroblastoma Cells
Abstract : The aim of this thesis has been to increase our understanding of the ion channel function and the ion transport mechanisms in glial cells. The analysis has also covered Na channel function in human neuroblastoma cells in order to get a basis for similar studies of glial cells In paper I isotopes 42K and 201 Tl were used to compare the K+ transport properties in cell lines from human malignant gliomas (U-251MG and Tp-378MG), carcinomas, and brain metastasis. READ MORE
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4. Auditory organotypic cultures and progenitor cell implantation
Abstract : According to the WHO, about 5 % of the world’s population suffers from disabling hearing loss. In people above the age of 65 the number is more than 30 %. Common effects of this condition are poor speech discrimination and impaired communication abilities. Patient surveys show that hearing loss often leads to a diminished quality of life. READ MORE
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5. Exploring Direct Conversion of Human Glia into Therapeutic Neurons
Abstract : Direct neuronal reprogramming of a somatic cell into therapeutic neurons, without a transient pluripotent state, provides new promise for the large number of individuals afflicted by neurodegenerative diseases or brain injury. This approach could be potentially applied directly in the brain by targeting resident cells as a source of new neurons. READ MORE