Search for dissertations about: "glomerular endothelium"

Showing result 6 - 8 of 8 swedish dissertations containing the words glomerular endothelium.

2. 6. Effects of PDGF-B gene inactivation in endothelial cell

   Author : Mattias Bjarnegård; Göteborgs universitet; []
   Keywords : gene targeting; Cre loxP; PDGF; pericyte; mouse; microangiopathy;

   Abstract : Platelet-derived growth factor-B (PDGF-B) is expressed by endothelial cells, neurons, macrophages and platelets. The relative importance of these cellular PDGF-B sources in vivo has been addressed by the creation of a conditional PDGF-B allele, which in the presence of a specific recombinase can be silenced in different tissues. READ MORE

4. 7. Expression profiling of blood vessels in pericyte deficiency and diabetes

   Author : Jenny Norlin; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The kidney glomerulus is essential for the filtration of waste products from the blood into the urine and in controlling the volume and composition of body fluids. Injury to the glomerulus can lead to altered glomerular filtration rate, proteinuria, thickening of the glomerular basement membrane (GBM) and accumulation of mesangial cell matrix. READ MORE

5. 8. Identification and characterization of kidney glomerulus-associated genes and proteins

   Author : Ljubica Perisic; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The kidney glomerulus is a micro-organ comprised of a molecular filtration barrier that prevents the loss of blood proteins into the primary filtrate. This function is dependent on the coordination of its three constituent layers: the endothelium, the glomerular basement membrane and the podocytes. READ MORE