Search for dissertations about: "glucose"

Showing result 1 - 5 of 878 swedish dissertations containing the word glucose.

  1. 1. Glucose and lipid metabolism in insulin resistance an experimental study in fat cells

    University dissertation from Umeå : Folkhälsa och klinisk medicin

    Author : Jonas Burén; Umeå universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; adipocyte; insulin resistance; type 2 diabetes; insulin signalling; glucose uptake; insulin; glucose; dexamethasone; insulin receptor substrate; protein kinase B; GLUT4; lipoprotein lipase; Folkhälsomedicin; MEDICINE Social medicine Public health medicine research areas; MEDICIN Socialmedicin Folkhälsomedicinska forskningsområden; medicin; Medicine;

    Abstract : Type 2 diabetes is usually caused by a combination of pancreatic β-cell failure and insulin resistance in target tissues like liver, muscle and fat. Insulin resistance is characterised by an impaired effect of insulin to reduce hepatic glucose production and to promote glucose uptake in peripheral tissues. READ MORE

  2. 2. Pharmacometrics Modelling in Type 2 Diabetes Mellitus Implications on Study Design and Diabetes Disease Progression

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Siti Maisharah Sheikh Ghadzi; Uppsala universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometric; type 2 diabetes mellitus; impaired glucose tolerance; prediabetes; anti-diabetes drug development; insulin; glucose; natural diabetes disease progression; lifestyle intervention; short-term provocation; long-term effect; glucose homeostasis; glucose and insulin regulation; weight; dropout; Farmaceutisk vetenskap; Pharmaceutical Science; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

    Abstract : Pharmacometric modelling is widely used in many aspects related to type 2 diabetes mellitus (T2DM), for instance in the anti-diabetes drug development, and in quantifying the disease progression of T2DM.The aim of this thesis were to improve the design of early phase anti-diabetes drug development studies with the focus on the power to identify mechanism of drug action (MoA), and to characterize and quantify the progression from prediabetes to overt diabetes, both the natural progression and the progression with diet and exercise interventions, using pharmacometrics modelling. READ MORE

  3. 3. Development of Flourescence-based Immunosensors for Continous Carbohydrate Monotoring Applications for Maltose and Glucose

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Henrik Engström; Högskolan i Kalmar.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carbohydrate; Diabetes; Immunosensor; Glucose; Maltose; Weak affinity chromatograhpy; Kolhydrater; Glukos; Maltose; Affinitetskromatografi; Diabetes; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; Bioteknik; Biotechnology;

    Abstract : Weak affinity interaction of monoclonal antibodies and carbohydrate antigens can be detected and quantified by alterations in the antibodies' intrinsic tryptophan fluorescence. These weak/transient binding events have been monitored by total internal reflection fluorescence (TlRF) by facilitating the change in intrinsic tryptophan fluorescence. READ MORE

  4. 4. Beta-glucose 1-phosphate interconverting enzymes in Lactococcus lactis: physiological role and regulation in maltose, trehalose and glucose metabolism

    University dissertation from Birgit Johansson, secretary at Applied Microbiology, Center for Chemistry and Chemical Engineering, Lund University

    Author : Ulrika Andersson; Lunds universitet.; Lund University.; [2002]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; Biochemical technology; Biokemisk teknik; bacteriology; Microbiology; Kemiteknik och kemisk teknologi; Chemical technology and engineering; trehalose 6-phosphate phosphorylase; beta-phosphoglucomutase; maltose phosphorylase; glucose; trehalose; maltose; Lactococcus lactis; beta-glucose 1-phosphate;

    Abstract : Lactic acid bacteria (LAB), including Lactococcus lactis, are abundant in nature. These bacteria convert carbohydrates into mainly lactate by a rather uncomplicated metabolism. An improved understanding of the physiological and genetical mechanisms involved in carbohydrate metabolism and its regulation will improve the industrial use of LAB. READ MORE

  5. 5. Oxidative stress and inflammation as a response to glucose exposure and dialysis

    University dissertation from Department of Nephrology, Lund University

    Author : Anna Bryland; Lunds universitet.; Lund University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucose; glucose degradation products; dialysis; diabetes; oxidative stress; inflammation; endothelial dysfunction;

    Abstract : Abstract: The main player of this thesis is glucose, both on a cellular level and with a clinical approach. Too much or wrongly handled glucose contributes to increased inflammation and oxidative stress, which is reinforced by the negative influences of uraemia and dialysis treatment. READ MORE