Search for dissertations about: "granulosa cells"

Showing result 1 - 5 of 25 swedish dissertations containing the words granulosa cells.

  2. 1. Regulation of apoptosis and steroidogenesis in ovarian preovulatory granulosa cells

    Author : Eva Svensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; granulosa cells; luteinizing hormone; progesterone receptor; RU 486; Org 31710; leptin; steroidogenesis;

    Abstract : Only a minute fraction of ovarian follicles present in a foetal ovary will complete the path to ovulation. The majority of the follicles will instead undergo atresia, a hormonally controlled apoptotic process. Apoptosis occurs throughout follicle development, with an extensive reduction in the number of follicles present at birth. READ MORE

  4. 2. Granulosa cell apoptosis: Transcriptional regulation by the nuclear progesterone receptor

    Author : P. Anders Friberg; Göteborgs universitet; []
    Keywords : ovary; granulosa cells; ovulation; luteinization; progesterone; apoptosis; cholesterol synthesis; isoprenylation;

    Abstract : Ovarian follicle atresia caused by granulosa cell apoptosis is a central process in normal female physiology. Progesterone has been reported to be a survival factor in granulosa cells at several developmental stages. READ MORE

  5. 3. Molecular pathways mediating the development of female germ cells

    Author : Sanjiv Risal; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Ovary; primordial follicles; primordial germ cells; Oogonial stem cells;

    Abstract : In mice, primordial germ cells (PGCs) dramatically increase in their number from 200 cells at 9.5 dpc to 10 000 cells at 12.5 dpc with doubling time of 12.6 hours. READ MORE

  6. 4. Progesterone receptor-mediated effects on apoptosis in periovulatory granulosa cells

    Author : Emilia Rung; Göteborgs universitet; []
    Keywords : ;

    Abstract : The most common fate of developing ovarian follicles is demise due to a process known as atresia. Regulation of atresia is dependent on the developmental stage of the follicles, resulting in a continuous reduction of the number of follicles as they differentiate and grow towards ovulation. READ MORE

  7. 5. Expression, regulation and fuction of small ubiquitin-related modifier-1. Interaction with nuclear proteins in vivo

    Author : Linus Ruijin Shao; Göteborgs universitet; []
    Keywords : SUMO-1; LH receptor; PR isoforms; caspase-3; DNA fragmentation; apoptosis; granulosa cells; HIF-1alpha; hypoxia; brain and heart;

    Abstract : The small ubiquitin-related modifier-1 (SUMO-1) is a 101-amino acid, ~12 kDa protein that is 18% identical to ubiquitin. Posttranslational covalent tagging of proteins with SUMO-1 (SUMOylation) serves many functions. For example, regulation of protein stability and modulation of transcriptional activation. READ MORE