Search for dissertations about: "growth enhancer"

Showing result 1 - 5 of 31 swedish dissertations containing the words growth enhancer.

  2. 1. Growth hormone in the brain : Focus on cognitive function

    Author : Erika Brolin; Fred Nyberg; Mathias Hallberg; Alfhild Grönbladh; Jörgen Isgaard; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; central nervous system; cognition; morphine; gamma-hydroxybutyrate; diabetes; Barnes maze; Morris water maze; mice; rats; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Cognitive impairments are an increasing health problem worldwide. In the developed countries, the average life expectancy has dramatically increased over the last decades, and with an elderly population more cases of cognitive impairments appear. READ MORE

  4. 2. The effects of growth hormone on opioid-induced toxicity in vitro

    Author : Erik Nylander; Mathias Hallberg; Alexis Bailey; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; opioids; methadone; morphine; ketobemidone; fentanyl; oxycodone; hydromorphone; insulin-like growth factor; cell viability; NG108-15; SH-SY5Y; hippocampus; cortex; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : There is an ongoing opioid crisis in the United States that is portrayed by a large number of opioid-related deaths. Many of these cases involve commonly used prescription opioids, such as morphine, oxycodone, fentanyl, and methadone. This is concerning and highlights the problems associated with long-term opioid treatment. READ MORE

  5. 3. The immunoglobulin heavy chain 3ʼ enhancer : coupling of basic-Helix-Loop-Helix proteins to the regulation of enhancer function

    Author : Velmurugesan Arulampalam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : During B lymphocyte development, the transcriptional activity of the IgH locus is subject to spatial and temporal changes. One cis-control element, the IgH 3' enhancer, has been implicated in regulating functional events in late B cell development. READ MORE

  6. 4. Transcriptional regulation of the platelet-derived growth factor B gene

    Author : Stephen J. Miller; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; Biology; Biologi; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Abstract : The Platelet-Derived Growth Factor B (PDGF-B) gene product is an important protein during development and adult life, as well as being associated with the development of many tumour types. It has been ascribed roles in many normal and pathological processes including angiogenesis, tissue repair, atherosclerosis and cytotrophoblast proliferation. READ MORE

  7. 5. Insulin-like growth factor 1 receptor, novel functions and future possibilities

    Author : Ahmed Waraky; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Insulin like growth factor-1 receptor (IGF-1R) has been shown to be important for cancer cell growth and survival, and is often overexpressed in malignant and premalignant tissues. Ligand binding to IGF-1R induces transphosphorylation and activation of the receptor, leading to subsequent activation of the phosphatidyl inositol-3 kinase (PI3K), the mitogen-activated protein kinase (MAPK) and the 14-3-3 pathways. READ MORE