Search for dissertations about: "guinea pig colon"

Found 5 swedish dissertations containing the words guinea pig colon.

  1. 1. Gastric and enteric Helicobacter species in animal models and in the human colon

    Author : Erik Sturegård; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; Mikrobiologi; bakteriologi; IL-10; Microbiology; bacteriology; virology; virologi; mykologi; hepatitis; colitis; IBD; inflammatory bowel disease; gastritis; animal model; mouse; guinea pig; Helicobacter ganmani; Helicobacter; Helicobacter pylori;

    Abstract : The Gram-negative genus of Helicobacter consists of many bacterial species that colonize a wide range of animal hosts. The genus can be divided into gastric species that colonize the stomach, and enteric species that preferentially colonize the colon and biliary tree of various animal hosts. READ MORE

  2. 2. Studies on nitric oxide in autonomic neurotransmission

    Author : Caroline Olgart; Karolinska Institutet; Karolinska Institutet; []
    Keywords : acetylcholine; autonomic neurotransmission; botulinum toxin; colon; guinea pig; ileum; intestine; nitric oxide; rat; tachykinin.;

    Abstract : The aim of the present thesis was to study nitric oxide (NO) as a mediator in autonomic neurotransmission in the enteric nervous system, including studies on the mechanism for neuronal release of NO, as well as the effects of NO on intestinal smooth muscle and enteric neurones. Furthermore, the signal transduction pathway for the evoked effects of NO and nitrergic neurotransmission were investigated. READ MORE

  3. 3. Nerve-induced release of nitric oxide in gastrointestinal and erectile tissue

    Author : Katarina Hallén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Autonomic neurotransmission; cyclic guanosine monophosphate; guinea pig colon; neuronal nitric oxide synthase; nitric oxide; nitrite; phosphodiesterase; rabbit corpus cavernosum; smooth muscle; soluble guanylate cyclase;

    Abstract : Nitric oxide (NO) is an important messenger of the autonomic nervous system, innervating the gastrointestinal and urogenital tracts among many other tissues. The aim of the present thesis was to study the nitrergic neurotransmission in enteric and erectile tissue with special emphasis on modulation of nitrergic neurotransmission by the soluble guanylate cyclase (sGC)/cyclic guanosine monophosphate (cGMP)-pathway. READ MORE

  4. 4. Neuronal release and function of nitric oxide in smooth muscle

    Author : Henrik H Iversen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Autonomic neurotransmission; gastrointestinal tract; nitric oxide; nitric oxidesynthase; smooth muscle; urinary tract.;

    Abstract : The aim of the present thesis was to study nitric oxide (NO) as an effector molecule in autonomic neurotransmission. The nitrergic transmitter was examined with regard to its pharmacological profile, stimuli of release, release pattern, and effects in gastrointestinal and urinary tract smooth muscle. READ MORE

  5. 5. Pharmacokinetics and inner ear transport of cisplatin

    Author : Victoria Hellberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Cisplatin is a commonly used platinum anti-cancer drug. Regrettably cisplatin has dose-limiting ototoxic side effects, e.g. the drug can induce an irreversible hearing loss. READ MORE