Search for dissertations about: "haitina"

Showing result 1 - 5 of 8 swedish dissertations containing the word haitina.

2. 1. Function, Pharmacology, Evolution and Anatomical Localization of G Protein-Coupled Receptors and Solute Carriers

   Author : Tatjana Haitina; Robert Fredriksson; Gert Flik; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Farmakologi; Medicine; medicin;

   Abstract : The G protein-coupled receptors (GPCRs) and solute carriers (SLC) are two large families of membrane-bound proteins. The aim of this study was to characterize these two families in terms of evolution and function. READ MORE

4. 2. Genetic studies of zebrafish muscles : clues to protection in muscle disease

   Author : Nils Dennhag; Fatima Pedrosa Domellöf; Jonas von Hofsten; Tatjana Haitina; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; zebrafish; muscle; extraocular muscles; intermediate filaments; bioinformatics; genetics; CRISPR Cas9; oftalmiatrik; ophthalmology; cellforskning; cell research;

   Abstract : Muscular dystrophies (MDs) are caused by dysregulation of over 40 proteins but commonly share features of muscle weakness, myofiber death and regeneration, loss of ambulation and premature death. A MD involves a broken link anywhere in the connection from extracellular matrix through the sarcolemma to the sarcomere. READ MORE

5. 3. Development and three-dimensional histology of vertebrate dermal fin spines

   Author : Anna Jerve; Per Erik Ahlberg; Martin Brazeau; Tatjana Haitina; Philippe Janvier; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; fin spine; paleontology; early vertebrate; histology; development; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

   Abstract : Jawed vertebrates (gnathostomes) consist of two clades with living representatives, the chondricthyans (cartilaginous fish including sharks, rays, and chimaeras) and the osteichthyans (bony fish and tetrapods), and two fossil groups, the "placoderms" and "acanthodians". These extinct forms were thought to be monophyletic, but are now considered to be paraphyletic partly due to the discovery of early chondrichthyans and osteichthyans with characters that had been previously used to define them. READ MORE

6. 4. Musculoskeletal Development in Jawed Vertebrates : Gene function, cis-regulation, and 3D phenotypes in zebrafish

   Author : Jake Leyhr; Tatjana Haitina; Sophie Sanchez; Per Ahlberg; Chrissy Hammond; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Nkx3.2; Gdf5; Mkx; zebrafish; jaw joint; skeleton; fin development; cartilage; tendon; ligament; enhancer; CRISPR Cas9; mutant; microCT; synchrotron; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

   Abstract : Vertebrate skeletons are an intricate framework of bony and cartilaginous structures that form through carefully orchestrated developmental processes, guided by interacting genetic pathways that regulate cellular differentiation, migration, and tissue morphogenesis. The specific timing and localisation of gene expression shapes the diverse array of skeletal elements, from the flexible cartilages of the embryonic stage to the hardened bones that provide structural support in adulthood, and the joints and connective tissues that articulate the musculoskeletal system. READ MORE

7. 5. Single-cell RNA sequencing as a tool to study panarthropod evolution

   Author : Brenda Irene Medina Jimenez; Ralf Janssen; Graham Budd; Tatjana Haitina; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Single-cell RNA sequencing; EvoDevo; gene expression; tissue dissociation; cell capture; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

   Abstract : Panarthropoda is a monophyletic group comprised of arthropods and lobopods, molting animals with a segmented body, paired appendages, dorsal brain, and ventral nerve cords. Evolutionary Developmental Biology (EvoDevo) is an interdisciplinary field that seeks to understand how changes in development form the basis for variations in morphology and phenotypic evolution, including the genetic network underlying these processes. READ MORE