Search for dissertations about: "heart muscle"

Showing result 1 - 5 of 180 swedish dissertations containing the words heart muscle.

2. 1. Heart Regeneration : Lessons from the Red Spotted Newt

   Author : Nevin Witman; Jamie Morrison; Thomas Braun; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Heart; Regeneration; Newt; microRNAs; RNA editing; Molecular Biology; molekylärbiologi;

   Abstract : Unlike mammals, adult salamanders possess an intrinsic ability to regenerate complex organs and tissue types, making them an exciting and useful model to study tissue regeneration. The aims of this thesis are two fold, (1) to develop and characterize a reproducible cardiac regeneration model system in the newt, and (2) to decipher the cellular and molecular underpinnings involved in regeneration. READ MORE

4. 2. Structure and function of the cytoskeleton in cardiac and skeletal muscle

   Author : Johanna Balogh; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP-receptor; Cardiovascular system; Kardiovaskulära systemet; cardiomyopathy; transgenic mice; skeletal muscle; heart; muscle contraction; cytoskeleton; desmin;

   Abstract : We have examined the functional and structural roles of the cytoskeletal protein desmin in cardiac and skeletal muscles using a genetically modified mouse (Des-/-) with the desmin gene ablated. Desmin forms filaments at the Z-disks in the striated muscle sarcomere, have connections to the sarcolemma and most likely align sarcomeres and whole cells. READ MORE

5. 3. The muscle cytoskeleton of mice and men : Structural remodelling in desmin myopathies

   Author : Lena Carlsson; Lars-Eric Thornell; Anders Arnér; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; desmin; nestin; synemin; paranemin; plectin; αB-crystallin; skeletal muscle; heart muscle; myotendinous junction; motor endplate; costamere; anatomi; Human Anatomy;

   Abstract : The muscle fibre cytoskeleton of skeletal and heart muscle cells is composed mainly of intermediate filaments (IFs), that surround the myofibrils and connect the peripheral myofibrils with the sarcolemma and the nuclear membrane. Desmin is the first muscle specific IF protein to be produced in developing muscles and is the main IF protein in mature muscles. READ MORE

6. 4. Being physically active as an adult with congenital heart disease

   Author : Annika Bay; Bengt Johansson; Kristina Lämås; Malin Berghammer; Camilla Sandberg; Anna Strömberg; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adult congenital heart disease; congenital heart disease; heart defect; physical activity; exercise self-efficacy; muscle function; quality of life; nursing; interviews; content analysis; prevention; omvårdnadsforskning med medicinsk inriktning; Caring Sciences;

   Abstract : Background: Due to advances in medical and surgical care adults with congenital heart disease (CHD) is a growing and aging population, that now outnumbers the children with CHD. In general, adults with CHD have reduced aerobic exercise capacity and nearly half of the patients do not reach current recommendations on physical activity. READ MORE

7. 5. Physical Activity and Cardiovascular Disease

   Author : Kasper Andersen; Johan Sundström; Claes Held; Frieder Braunschweig; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical activity; epidemiology; cohort study; heart failure; cardiovascular disease; arrhythmias; atrial fibrillation; bradyarrhythmias; sudden cardiac death; heart failure; stroke; ischemic heart disease; cardiovascular death; maximal exercise capacity; muscle strength; skeletal muscle morphology; Kardiologi; Cardiology; Epidemiology; Epidemiologi;

   Abstract : The aim was to investigate associations of fitness and types and levels of physical activity with subsequent risk of cardiovascular disease.Four large-scale longitudinal cohort studies were used. The exposures were different measures related to physical activity and the outcomes were obtained through linkage to the Swedish In-Patient Register. READ MORE