Search for dissertations about: "hematologic malignancies"

Showing result 1 - 5 of 21 swedish dissertations containing the words hematologic malignancies.

2. 1. Trisomies in Hematologic Malignancies

   Author : Kajsa Paulsson; Avdelningen för klinisk genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; Klinisk genetik; cytogenetik; Genetik; cytogenetics; Genetics; leukemia; chromosome aberration; trisomy;

   Abstract : Acquired clonal chromosome aberrations, closely associated with leukemogenesis, are found in many hematologic malignancies. Although the balanced rearrangements, such as translocations and inversions, are the ones most commonly thought of in the context of leukemias, gains of chromosomes ? e.g.. READ MORE

4. 2. Clinical - cytogenetic correlations in malignant hematologic disorders

   Author : Nils Mauritzson; Avdelningen för hematologi och transfusionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; treatment-related.; prognosis; gender; age; morphology; Karyotype; hematologic malignancies; extracellulära vätskor; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

   Abstract : In the present thesis, clinicogenetic correlations are investigated in a large population-based series of acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), acute lymphoblastic leukemia, and chronic myeloid leukemia, for which the karyotypes were analyzed at the same center. The karyotypic pattern, i.e. READ MORE

5. 3. Sexuality in patients treated for hematologic malignancies - Problems and need for support from patients’ and nurses’ perspectives

   Author : Cecilia Olsson; Maria Larsson; Ann-Kristin Sandin-Bojö; Kaisa Bjuresäter; Karin Ahlberg; Karlstads universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer patients; hematologic malignancies; nursing; nurse-patient communication; support; sexuality; body image; health related quality of life; Nursing Science; Omvårdnad;

   Abstract : Aim: The overall aim of this thesis was to describe and explore how sexuality, body image and HRQoL were affected in patients treated for hematologic malignancies, and their need for support. A further aim was to describe nurses’ conceptions of dialogues about sexuality. READ MORE

6. 4. Computational biology of blood disorders: Patterns and algorithms

   Author : Björn Nilsson; Institutionen för laboratoriemedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; Klinisk genetik; Image analysis; Ontological analysis; Pattern recognition; Gene expression profiling; Microarrays; Hematologic malignancies; Acute leukemia; Chronic myeloid leukemia;

   Abstract : The morphological and molecular characterization and of malignant blood disorders is pivotal to ensure a correct diagnosis, guide therapy, and, in the longer term, to identify their molecular causes. Over the past several years, new technology has increased our abilities to describe, typecast, and understand hematologic malignancies beyond what was previously possible. READ MORE

7. 5. Gene Expression Studies of Hematologic Malignacies

   Author : Anna Andersson; Avdelningen för klinisk genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; cancer; onkologi; Cytologi; oncology; Cytology; acute myeloid leukemia; acute lymphoblastic leukemia; normal hematopoietic cells; cDNA microarray; gene expression profiling; hematopoiesis; pediatric leukemia; fusion gene; Pediatrics; Pediatri; Clinical genetics; Klinisk genetik; cancerology; Hematologi; extracellulära vätskor;

   Abstract : The general aim of this thesis was to characterize hematologic malignancies using gene expression profiling in order to obtain an improved classification and to study deregulated transcriptional networks in leukemia. In the first study (Article I), the gene expression profiles of hematologic cell lines were analyzed to investigate whether such cell lines maintain expression profiles that are characteristic of their primary genetic changes. READ MORE