Search for dissertations about: "hinge domain"

Showing result 1 - 5 of 10 swedish dissertations containing the words hinge domain.

  2. 1. Structure-function relationships of hormone-sensitive lipase

    Author : Torben Österlund; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteins; mutagenesis; domain; fold; catalytic triad; lipase; structure; enzymology; Proteiner; enzymologi;

    Abstract : The primary role of hormone-sensitive lipase (HSL), an 84 kDa enzyme of 768 amino acids (in the rat protein), is to hydrolyse stored triacylglycerols in adipocytes of white adipose tissue. Catecholamines and insulin regulate lipolysis through cellular signalling. READ MORE

  4. 2. On an Efficient Method fo Time-Domain Computational Aeroelasticity

    Author : David Eller; Ulf Ringertz; Paolo Mantegazza; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; aeroelasticity; unsteady aerodynamics; boundary element method; multidisciplinary simulation; Vehicle engineering; Farkostteknik;

    Abstract : The present thesis summarizes work on developing a method for unsteady aerodynamic analysis primarily for aeroelastic simulations. In contrast to widely used prediction tools based on frequency-domain representations, the current approach aims to provide a time-domain simulation capability which can be readily integrated with possibly nonlinear structural and control system models. READ MORE

  5. 3. NMR STUDIES ON STRUCTURE AND DYNAMICS OF TWO-DOMAIN PROTEINS

    Author : Houman Ghasriani; Biofysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fysikalisk kemi; Biochemistry; Metabolism; Biokemi; metabolism; Physical chemistry; Molekylär biofysik; CRISP-3; NMR; 3D-structure; NMR relaxation; Molecular biophysics; Prostate cancer; EGF module; PSP94; Beta-microseminoprotein; Protein S;

    Abstract : The general objective of the present thesis work was to examine 3-dimensional structure as well as the motional properties of two different types of two-domain proteins by solution-state NMR. One of the major tasks of this thesis work was to investigate the domain orientation of these molecules by employing residual dipolar couplings (RDC) which can be used as orientational restraints for increasing the accuracy of protein structures determined by NMR. READ MORE

  6. 4. Structural studies on the extracellular flavocytochrome cellobiose dehydrogenase from Phanerochaete chrysosporium

    Author : Martin Hällberg; Andrea Mattevi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; cellobiose dehydrogenase; flavocytochrome; hydride transfer; radical mechanism; X-ray crystallography; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Biology; with specialization in structural biology; biologi; med inriktning mot strukturbiologi;

    Abstract : Microorganisms that degrade lignocellulose play an important role in maintaining the global carbon cycle. Under cellulolytic conditions, the fungus Phanerochaete chrysosporium produces an extracellular flavocytochrome, cellobiose dehydrogenase (CDH), with a proposed role in lignocellulose degradation. READ MORE

  7. 5. Structural aspects of binding and transport proteins : By Barnali Neel Chaudhuri

    Author : Barnali Neel Chaudhuri; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Binding and transport proteins are essential for the transport of nutrients, vitamins, hormones, pheromones, etc. to their target destinations. Lipid-binding proteins typically contain an internal cavity where the hydrophobic/amphipathic ligands bind. Transport proteins with binding clefts for water-soluble sugars have different architectures. READ MORE