Search for dissertations about: "histone modification as epigenetic neurodegeneration"

Found 1 swedish dissertation containing the words histone modification as epigenetic neurodegeneration.

2. 1. 24s-Hydroxycholesterol : studies on regulatory mechanisms behind its formation in the brain and its potential use as a marker for neurodegeneration

   Author : Marjan Shafaati; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cholesterol 24-hydroxylase (CYP46A1) belongs to the cytochrome P450 super family and is responsible for conversion of cholesterol to the oxysterol 24S- hydroxycholesterol (24S-OHC). This structural modification allows 24S-OHC to traverse the blood brain barrier and this pathway is the major one for elimination of cholesterol from the mammalian brain. READ MORE