Search for dissertations about: "homology detection"
Showing result 1 - 5 of 18 swedish dissertations containing the words homology detection.
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1. Protein structure prediction : Zinc-binding sites, one-dimensional structure and remote homology
Abstract : Predicting the three-dimensional (3D) structure of proteins is a central problem in biology. These computationally predicted 3D protein structures have been successfully applied in many fields of biomedicine, e.g. family assignments and drug discovery. READ MORE
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2. Sequence-based predictions of membrane-protein topology, homology and insertion
Abstract : Membrane proteins comprise around 20-30% of a typical proteome and play crucial roles in a wide variety of biochemical pathways. Apart from their general biological significance, membrane proteins are of particular interest to the pharmaceutical industry, being targets for more than half of all available drugs. READ MORE
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3. Hidden Markov models for remote protein homology detection
Abstract : Genome sequencing projects are advancing at a staggering pace and are daily producing large amounts of sequence data. However, the experimental characterization of the encoded genes and proteins is lagging far behind. READ MORE
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4. Detection and characterization of novel proteins in Trypanosoma cruzi
Abstract : Trypanosoma cruzi is a flagellated protozoan parasite. It infects a wide range of mammals, including humans. Human T. cruzi infections are endemic to South and Central America. READ MORE
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5. Interaction engineered three-helix bundle domains for protein recovery and detection
Abstract : HTML clipboard The great advances in DNA technology, e.g. sequencing and recombinant DNA techniques, have given us the genetic information and the tools needed to effectively produce recombinant proteins. Recombinant proteins are valuable means in biotechnological applications and are also emerging as alternatives in therapeutic applications. READ MORE