Search for dissertations about: "hormone secretion"

Showing result 1 - 5 of 193 swedish dissertations containing the words hormone secretion.

  2. 1. The Role of Protein Kinase C in the Extracellular Ca2+-regulated Secretion of Parathyroid Hormone

    Author : Amos M. Sakwe; Lars Rask; Claes Juhlin; Uppsala universitet; []
    Keywords : Medical sciences; parathyroid hormone; Ca2 ; protein kinase C; calcium sensing receptor; ERK1 2; biosynthesis; secretion; MEDICIN OCH VÅRD; MEDICINE; MEDICIN;

    Abstract : Parathyroid hormone (PTH) is the major physiological regulator of the extracellular Ca2+ concentration ([Ca2+]o) in the body. The secretion of this hormone is suppressed at high [Ca2+]o. READ MORE

  4. 2. Signal Transduction of Glucagon Secretion

    Author : Elaine Vieira; Erik Gylfe; Lena Eliasson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; secretion; glucagon; store-operated channels; calcium; diabetes; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : Diabetes mellitus is a bihormonal disorder with hyperglycemia due to deficiency of insulin and hypersecretion of glucagon. To improve diabetes treatment it is important to clarify the signal transduction of glucagon secretion. READ MORE

  5. 3. Origin, release and functional significance of the novel gastric hormone ghrelin

    Author : Charlotta Dornonville de la Cour; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; pharmacognosy; pharmacy; Pharmacological sciences; bone metabolism; energy homeostasis; glucagon; insulin; secretion; pancreastatin; somatostatin; histamine; gastrin; gastric acid secretion; ghrelin; gastric motility; A-like cells; farmakognosi; farmaci; toxikologi;

    Abstract : The novel gastric hormone ghrelin was discovered by virtue of its ability to release growth hormone (GH) via interaction with the so-called GH-secretagogue receptor (GHS-R). Earlier only synthetic agents were known to bind with the GHS-R, hence, ghrelin is the first identified endogenous ligand. READ MORE

  6. 4. Cardiovascular effects of growth hormone, IGF-I and growth hormone secretagogues

    Author : Åsa Tivesten; Göteborgs universitet; []
    Keywords : cardiovascular system; growth hormone; insulin-like growth factor-I; growth hormone secretagogues; echocardiography.;

    Abstract : Growth hormone (GH) may exert direct growth-promoting and metabolic actions on target tissues, but most of its effects are mediated by circulating (endocrine) or local (auto-/paracrine) insulin-like growth factor-I (IGF-I). The GH/IGF-I system has an important role during cardiac development and for maintaining the structure and function of the heart. READ MORE

  7. 5. Identification of novel growth hormone-regulated factors

    Author : Björn Andersson; Göteborgs universitet; []
    Keywords : Growth hormone; idiopathic short stature; growth hormone deficient; prepubertal; children; genomic; proteomic;

    Abstract : The studies described in this thesis aimed to identify novel factors involved in the regulation of longitudinal growth and bone mineralization in response to growth hormone (GH) treatment. This was done by performing a single factor study (Paper I) where it was found that growth response was negatively correlated with adiponectin levels during the first year of GH treatment in short prepubertal children. READ MORE