Search for dissertations about: "human adenovirus"

Showing result 1 - 5 of 78 swedish dissertations containing the words human adenovirus.

  2. 1. Human adenoviruses : new bioassays for antiviral screening and CD46 interaction

    Author : Emma Andersson; Göran Wadell; Sigvard Olofsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; CD46; hemagglutination; antiviral; small molecule; screening; Virology; Virologi;

    Abstract : Adenoviruses are common pathogens all over the world. The majority of the population has at some point been infected with an adenovirus. Although severe disease can occur in otherwise healthy individuals an adenovirus infection is most commonly self limited in these cases. READ MORE

  4. 2. Human adenovirus – host cell interplay : The role of the cellular zinc finger proteins and mitochondrial DNA

    Author : Kwangchol Mun; Tanel Punga; Stefan Schwartz; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Adenovirus; Protein VII; Ubiquitination; Chromatin remodeling; Mitochondria;

    Abstract : Human adenovirus (HAdV) is an abundant DNA virus with significant clinical relevance since it cauces a variety of respiratory, ocular, and gastrointestinal diseases. It is also intensively used as a therapeutic tool to treat cancers and to boost immune responses. READ MORE

  5. 3. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification

    Author : Di Yu; Magnus Essand; Dirk Nettelbeck; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; cancer; therapy; neuroblastoma; neuroendocrine; modification; Tat; PTD; cell penetrating peptide; Helicobacter pylori; NAP; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Klinisk virologi; Clinical Virology; Medical Virology; Medicinsk virologi; Molekylär medicin; Molecular Medicine; Molekylär bioteknik; Molecular Biotechnology;

    Abstract : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. READ MORE

  6. 4. Virion- and VAP-receptor recognition in the human adenovirus type 2 system

    Author : Eduardo Rodriguez; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; T7pol-M13; adenovirus fiber shaft fragment; receptor recirculation; lysosomotropic agents; Adenovirus; HeLa cells; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : This thesis is focused on the early steps of a complex virus-cell interaction. The human adenovirus type 2 (HAdV-2) infects permissive cells, by first recognizing a protein of the immunoglobulin superfamily that serves as the Coxsackie and adenovirus receptor (CAR). This attachment step is mediated by the adenovirus fiber protein. READ MORE

  7. 5. Mapping viruses in non-malignant tonsils, nasal polyps, sinonasal inverted papilloma and laryngeal cancer

    Author : Alexandra Schindele; Katarina Olofsson; Karin Nylander; Annika Allard; Lalle Hammarstedt Nordenvall; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papilloma virus; Epstein-Barr virus; Human cytomegalovirus; Human adenovirus; p16 tumor suppressor protein; Non-malignant tonsillar disease; Chronic rhino sinusitis with nasal polyps; sinonasal inverted papilloma; laryngeal cancer; EBER-ISH; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Abstract : Background: The upper respiratory tract is exposed to viruses, which can lead to infection and cancer development. We chose to study common and/or chronic diseases along with common and cancer related viruses in the upper airway. READ MORE