Search for dissertations about: "human cardiomyocyte"

Showing result 1 - 5 of 15 swedish dissertations containing the words human cardiomyocyte.

  2. 1. Cardiomyocyte Cell Cycle, Renewal and Isolation

    Author : Stuart Walsh; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; binucleation; Cardiomyocytes; surface marker; troponin-T; mitosis; microarray; cell cycle; FACS;

    Abstract : Heart disease results from the loss of cardiomyocytes following myocardial damage and is a leading cause of death worldwide. Stimulating the endogenous regeneration of cardiomyocytes or isolating them from in vitro culture is an attractive therapeutic strategy. READ MORE

  4. 2. Transcriptional profiling of human embryonic stem cells and their functional derivatives

    Author : Jane Synnergren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; transcription; differentiation; human embryonic stem cells; gene expression; Naturvetenskap;

    Abstract : Human embryonic stem cells (hESCs) represent populations of pluripotent, undifferentiated cells with unlimited replication capacity, and with the ability to differentiate into any functional cell type in the human body. Based on these properties, hESCs and their derivatives provide unique model systems for basic research on embryonic development. READ MORE

  5. 3. Cytoarcheology : understanding cellular turnover in the human brain and heart

    Author : Ratan Dev Bhardwaj; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The total number of cells within a human being increases dramatically during growth, yet certain organs are thought to have distinct differences within this regard. Just as cells may be added to an organ, cells may die also, and these dynamics of cellular addition and cellular death are known as cellular turnover. READ MORE

  6. 4. Identification and characterization of progenitor populations in the human adult heart

    Author : Joakim Sandstedt; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cardiac progenitor cells; heart; C-kit; Side Population; Stage Specific Embryonic Antigens; FACS;

    Abstract : Traditionally, the heart has been regarded as a non-regenerative organ. During the last 10 years, this notion has been challenged. By 14C measurements, it was calculated that at the age of 50, about 45% of all cardiomyocytes had formed after birth. READ MORE

  7. 5. Cell transplantation with human mesenchymal or embryonic stem cells to the heart : experimental, molecular, immunological and echocardiographic studies

    Author : Karl-Henrik Grinnemo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Human mesenchymal stem cells; human embryonic stem cells; human cardiomyocyte; Islet-1; Nkx2.5; stem cell; xenotransplantation; rejection; FoxP3 T-cells; tolerance; CTLA4Ig; anti- CD40L; LFA-1;

    Abstract : Background: Human mesenchymal stem cells (hMSC), human embryonic stem cells (HESC) and human fetal cardiomyocyte progenitor cells (HFCP) all represent possible candidate cells for regeneration of damaged myocardium. Although they represent cell types with many positive attributes, their capacity to engraft, to differentiate into mature cardiomyocytes, to improve myocardial function and their immunological properties are the focus of these studies. READ MORE