Search for dissertations about: "human cartilage"
Showing result 1 - 5 of 84 swedish dissertations containing the words human cartilage.
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1. Articular cartilage proteoglycan biosynthesis and sulfation
Abstract : Glucosamine (GlcN) and glucosamine sulfate (GS) have been used to treat the patients with osteoarthritis(OA) as a disease-modifying agent. Previousin vitro studies have focused on the effects of GlcN or GSon cartilage metabolism, whereas in vivo studies have investigated their potential for the treatment of OA. READ MORE
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2. Cartilage homeostasis: Modulation of cells and extracelllar matrix assembly
Abstract : The cartilage extracellular matrix consists of the collagen network which enmeshes the large aggregating proteoglycan, aggrecan. Accessory molecules regulate the formation and maintenance of these structures. This thesis studies aspects of cartilage assembly during development and its degradation in disease, focusing on the collagen network. READ MORE
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3. Mesenchymal Stem Cells in Tumor Growth Inhibition and Cartilage Differentiation
Abstract : The work presented in this thesis has been focused on mesenchymal stem cells (MSCs). In the two first studies, the effects of MSCs on tumor growth and development in vitro and in vivo was investigated. READ MORE
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4. Contrast-enhanced MRI of human knee cartilage Clinical applications of the novel dGEMRIC technique to study glycosaminoglycan content in articular cartilage
Abstract : Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a new technique to study cartilage glycosaminoglycan (GAG) content. The negatively charged contrast agent Gd-DTPA2-, injected intravenously, distributes in the cartilage inversely to the likewise negatively charged GAG. READ MORE
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5. In vivo Sub-regional dGEMRIC Analysis and Contrast Distribution in Clinical Studies of Human Knee Cartilage
Abstract : Aims: This work was carried out to investigate whether considering cartilage depth in vivo dGEMRIC would provide additional information on the molecular content and changes in normal and diseased cartilage. Methods: Study I was a longitudinal study on 23 healthy volunteers; Study II was a case-control study on 9 sedentary individuals and 8 elite runners. READ MORE