Search for dissertations about: "hypothyroid"

Showing result 1 - 5 of 10 swedish dissertations containing the word hypothyroid.

  2. 1. Thyroid hormone mediates fibroblast growth factor receptor expression, which both alter cell surface mechanical properties of the mammalian cochlea

    Author : Katherine B Szarama; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cells in the mammalian hearing organ, the cochlea, develop a specialized patterning and cellular architecture necessary for hearing function. Cytoskeletal components, such as actin and microtubules, maintain the material and mechanical properties of these cells. READ MORE

  4. 2. On the cerebrospinal fluid disposition and neurobiological role of cholecystokinin in man

    Author : Tove Gunnarsson; Conny Nordin; Erik Widerlöv; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Cholecystokinin (CCK) is the most abundant neuropeptide in the brain, where it acts as a neurotransmitter and neuromodulator. The tetrapeptide CCK-4 and the octapeptide CCK-8 have been implicated in various behavioural and physiological functions, such as anxiety, pain and satiety. READ MORE

  5. 3. Thyroid hormone receptors in liver metabolism

    Author : Hjalmar Gullberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Thyroid hormone has a profound impact on mammalian metabolism; hypothyroidism causes decreased metabolic rate and increased serum cholesterol levels. One major target organ for the hormone is the liver, the most important metabolic organ in mammals, that balances anabolism of carbohydrates and lipids against catabolism. READ MORE

  6. 4. The importance of thyroid function for female reproduction

    Author : Frida Hosseini Akram; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Thyroid dysfunction is one of the most common endocrine disorder. Thyroid dysfunction affects the female reproductive system and can be manifested by menstrual irregularities, pregnancy loss and infertility. Unexplained infertility has an incidence of 10 to 15 % worldwide. READ MORE

  7. 5. Hypothyroidism caused by a mutant thyroid hormone receptor alpha1 : consequences for development and physiology

    Author : Maria Sjögren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Lack of sufficient thyroid hormone during pregnancy and early postnatal development results in profound mental retardation and motor deficits whereas altered thyroid status in the adult is associated with disturbed metabolic homeostasis and impaired cardiac function. Thyroid hormone mediates its effects through the distinct thyroid hormone receptors (TR) TRalpha1 and TRbeta1-2, which are ligand-modulated transcription factors that regulate gene expression both in the presence and absence of hormone. READ MORE