Search for dissertations about: "iPLA 2"
Found 2 swedish dissertations containing the words iPLA 2.
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1. Biosynthesis of leukotriene B4 in hematological malignancies
Abstract : Leukotrienes (LT) are biologically active metabolites of the fatty acid arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA 2), this fatty acid can be converted to leukotrienes, lipoxins, prostaglandins or thromboxane. The conversion of AA to LTA 4 is catalyzed by five-lipoxygenase (5-LO). READ MORE
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2. The effect of intra-abdominal local anaesthetics following major gynaecological surgery. Clinical and experimental studies
Abstract : Background: Local anaesthetics (LA), in addition to inhibition of pain signalling, also have anti-inflammatory properties. In vitro studies have demonstrated anti-proliferative and cytotoxic effect of LAs on cancer cells when administered in therapeutic concentrations. READ MORE