Search for dissertations about: "igf-i"
Showing result 1 - 5 of 161 swedish dissertations containing the word igf-i.
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1. Insulin and IGF-I in type 1 diabetes
Abstract : Patients with type I diabetes have alterations in the GH/IGF system with reduced levels of circulating IGF-I, as well as other disturbances in the components of the IGF system.Alterations of both local and circulating IGF-I and its binding proteins (IGFBPs) have been associated with metabolic and vascular manifestations of diabetes and also with atherosclerosis. READ MORE
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2. Effects of GH and liver-derived IGF-I on growth and metabolism
Abstract : Growth hormone (GH) exerts major effects on body growth and metabolism. Insulin-like growth factor (IGF) is expressed in response to GH and is known to mediate many of the effects of GH. The largest expression of IGF is found in the liver although it is expressed in virtually every tissue of the body. READ MORE
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3. Life, death ant the role of IGF-I in human multiple myeloma
Abstract : Multiple myeloma (MM) is a clonal expansion of malignant cells with a plasmablast- plasma cell morphology in the bone marrow. It is a fatal disease with a median survival of 2-3 years after start of conventional therapy. READ MORE
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4. Connexin43 in astroglial gap junctions. Regulation by age, neurotransmitters, GH and IGF-I
Abstract : Connexins form gap junctions that are aqueous pores allowing low-molecular (.... READ MORE
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5. Proliferative and protective effects of the GH/IGF-I axis on cardiomyocytes and neural progenitor cells
Abstract : Cardiovascular disease is the most common cause of mortality in the Western world and the majority of cardiovascular deaths are caused by coronary artery disease or cerebrovascular disease. Growth hormone (GH) is a growth-promoting hormone synthesized by the pituitary. READ MORE