Search for dissertations about: "immunology"

Showing result 6 - 10 of 832 swedish dissertations containing the word immunology.

  2. 6. The mast cell transcriptome and the evolution of granule proteins and Fc receptors

    Author : Srinivas Akula; Lars Hellman; Sandra Kleinau; Arne Egesten; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cell; Fc receptors; Granule serine protease; Evolution and transcriptome.; Immunologi; Immunology;

    Abstract : Protection against disease-causing pathogens, known as immunity, involves numerous cells organs, tissues and their products. To able to understand the biology of immune cells (hematopoietic cells) and their role in an immune system, we have used several different methods, including transcriptome analyses, bioinformatics, production of recombinant proteins and analyses of some of them, focusing on the granule proteases by substrate phage display. READ MORE

  4. 7. The Impact of Tryptase and Epigenetic Mechanisms on Mast Cells

    Author : Sultan Alanazi; Gunnar Pejler; Constantin Urban; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mast cells; mastocytosis; tryptase; histone; DNA; methylation; neutrophil extracellular traps; Immunologi; Immunology;

    Abstract : Mast cells have a large influence on multiple immune-mediated responses, including allergic conditions, and they have been implicated in various diseases such as arthritis and cancer. Mastocytosis is characterized by abnormal mast cell proliferation induced by mutations in KIT, the stem cell factor (SCF) receptor. READ MORE

  5. 8. Immunologic aspects of the pathogenesis of human onchocerciasis

    Author : Magdi Mahmoud Ali; Klavs Berzins; Norbert Brattig; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi;

    Abstract : Onchocerciasis, or river blindness, is a parasitic disease that affects more than 20 million people globally. The induction of pathology is directly related to the presence and destruction of the microfilarial stages (mf) of this filarial nematode. READ MORE

  6. 9. Maternal immune characteristics and innate immune responses in the child in relation to allergic disease

    Author : Petra Amoudruz; Eva Sverremark-Ekström; Zsolt Szépfalusi; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Abstract : The mechanistic factors responsible for the increase in allergic diseases are still not fully understood, but a reduced microbial stimulation seems to be one of the key issues. Research is now aiming at investigating the relationship between the innate immune system, involving the toll-like receptors, and allergy development. READ MORE

  7. 10. Monoclonal antibodies to human interferon-α and interferon-γ : Characterization and application with focus on interferon-γ as a T cell cytokine

    Author : Gudrun Andersson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

    Abstract : The major functions of the immune system are to combat infections and to control that normal auto-immunity does not turn into auto-aggression. Antibodies, together with T cell receptors and MHC molecules, dictates the immunological specificity. READ MORE