Search for dissertations about: "immunosuppression"

Showing result 16 - 20 of 172 swedish dissertations containing the word immunosuppression.

2. 16. Opportunistic viral infection after paediatric transplantation

   Author : Carola Kullberg-Lindh; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Paediatric liver transplantation; paediatric stem cell transplantation; immunosuppression; opportunistic; CMV; EBV; AdV; HHV-6; real-time PCR; monitoring; specimen; post transplant lymphoproliferative disease;

   Abstract : Background: Opportunistic viral infections can cause considerable morbidity and mortality in organ and stem cell transplanted (SCT) patients, mainly due to iatrogenic T cell dysfunction. Whereas in SCT patients, in general the immunosuppressive treatment can be discontinued after 6-12 months, for the majority of organ transplanted patients, the need for treatment is life-long. READ MORE

4. 17. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

   Author : Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

   Abstract : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. READ MORE

5. 18. Regulatory T cells and mucosal-associated invariant T cells in colon adenocarcinomas; Phenotype and function

   Author : Filip Ahlmanner; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colon cancer; regulatory T cells; CD39; adenosine; immune checkpoint molecules; immunosuppression; MAIT cells; cytokines; cancer-specific survival;

   Abstract : In many solid cancers, and also in colon adenocarcinomas, an increased accumulation of lymphocytes is beneficial for the patient. However, tumor-infiltrating immune cells may be either pro- or anti-tumorigenic and the balance between these two counteracting forces partly determines patient outcome. READ MORE

6. 19. Studies of Regulatory T cells with Implications for Clinical Applications

   Author : Marcus Bergström; Olle Korsgren; Wayne Hawthorn; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regulatory T cell; Treg; Transplantation; Immunology; Tolerance; Islet transplantation; Immunosuppression; Immunologi; Immunology;

   Abstract : Regulatory T cells (Tregs) are vital for regulating immune homeostasis and for preventing immunopathology. The immunosuppressive functions of Tregs have raised hope for their potential use in clinical applications. READ MORE

7. 20. Neoehrlichia mikurensis in Sweden : An emerging tick-borne human pathogen

   Author : Lisa Labbé Sandelin; Björn Olsen; Jonas Waldenström; Per-Eric Lindgren; Ivar Tjernberg; Lars Hagberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neoehrlichia; Tick-borne Infections; Transfusion-transmitted infections; Bacterial Zoonotic infections; Blood Donors; Immunosuppression; Infectious Diseases; Emerging; Blood Safety; Bird Migration; Infektionssjukdomar; Infectious Diseases;

   Abstract : Neoehrlichia mikurensis is an emerging tick-borne human pathogen, causing neoehrlichiosis in immunosuppressed and immunocompetent individuals. It targets the vascular endothelium, leading to thromboembolic and vascular events, but can also pass without symptoms. READ MORE