Search for dissertations about: "in situ hybridisation"

Showing result 11 - 15 of 63 swedish dissertations containing the words in situ hybridisation.

  2. 11. Studies of presenilin function in neurodegeneration and in human embryonic CNS during development

    Author : Beata Kostyszyn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Presenilin-1 (PS1) and -2 (PS2) gene mutations cause early onset familial Alzheimer's disease (FAD). Presenilins provide gamma-secretase activity for cleaving transmembrane proteins such as the amyloid precursor protein (APP), Notch receptors and ligands. READ MORE

  4. 12. Anaerobic Digestion – Microbial Ecology, Improved Operational Design and Process Monitoring

    Author : Marika Murto; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; monitoring; UASB; Biotechnology; Bioteknik; methanogens; fluorescence in situ hybridisation; FISH; co-digestion; biogas; biofilm; aqueous two phase system; anaerobic digestion; 16S rDNA; alkalinity;

    Abstract : The implementation of anaerobic digestion is important in the concept of sustainable development, especially regarding the environmental benefits. Biogas is produced when organic matter is degraded by microorganisms under oxygen-free (anaerobic) conditions. READ MORE

  5. 13. Characterisation of chromosomal aberrations in childhood leukaemia

    Author : Ann Nordgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chromosome aberrations; SKY; interphase-FISH; Childhood ALL;

    Abstract : Acute lymphoblastic leukaemia (ALL) is the most common malignancy in childhood, accounting for approximately 25% of all paediatric malignancies. Based on clinical risk criteria and modem laboratory investigations including immunophenotyping, cytogenetics, and molecular genetics, patients can be divided into prognostic groups and assigned to risk- adjusted treatment protocols. READ MORE

  6. 14. Genetic studies in early embryos with emphasis on preimplantation genetic diagnosis

    Author : Erik Iwarsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : chromosomal abnormality 1 embryo fluorescent in situ hybridisation FISH 1 in vitro fertilisation IVF 1 preimplantation genetic diagnosis PGD ;

    Abstract : It has been estimated that as much as 70-80% of all human conceptions do not develop to term. A majority of clinically recognisable pregnancies, which are miscarried, contain chromosome abnormalities. However, data from very early embryo development are difficult to obtain. READ MORE

  7. 15. Brain Stem Involvement in Immune and Aversive Challenge

    Author : Jakob Paues; Anders Blomqvist; Finn Hallböök; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipopolysaccharide; Lithium Chloride; anorexia; aversion; parabrachial; brain stem; melanocortin; CGRP; enkephalin; Neurobiology; Neurobiologi;

    Abstract : Activation of the immune system by e.g. bacteria induces the acute-phase-response and sickness behaviour. The latter encompasses among other things fever, lethargy, anorexia and hyperalgesia. READ MORE