Search for dissertations about: "in situ hybridisation"

Showing result 16 - 20 of 63 swedish dissertations containing the words in situ hybridisation.

  2. 16. Studies on the cytokine network in multiple sclerosis

    Author : Pia Kivisäkk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is considered to be an inflammatory immune-mediated disease of the central nervous system (CNS), the aetiology of which remains enigmatic. Cytokines produced by infiltrating inflammatory cells and resident cells in the brain are proposed to play a major role in directing and regulating the immune response, as well as mediating tissue damage. READ MORE

  4. 17. The role of substance P in respiratory control in the newborn : effects of morphine and nicotine

    Author : Jonas Berner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : We breathe in order to maintain oxygen, carbon dioxide and pH levels within the physiological range in response to the metabolic demands of the body. To achieve this, the respiratory control system is dependent on input from peripheral and/ central chemosensitive areas and on participation of different neuromodulator systems. READ MORE

  5. 18. The CHD chromatin remodeling factors in schizosaccharomyces pombe

    Author : Julian Walfridsson; Karl Ekwall; Pernilla Bjerling; Stefan Björklund; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Regulation of chromatin structure is essential in a wide variety of processes including transcriptional regulation, recombination, replication, chromosome segregation, development and differentiation. The enzymes that are central in regulating chromatin structure can be classified into two major groups. READ MORE

  6. 19. Invasion promoting factors in endometriotic and endometrial tissue

    Author : Christina Bruse; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Endometriosis; endometrium; PF; tPA; uPA; uPAR; PAI-1; PAI-2; IL-1beta; IL-6; TNFalpha.;

    Abstract : Endometriosis is a common gynaecologic disorder, affecting women of fertile age with pelvic pain and infertility, and is characterized by the presence of endometrial glands and stroma outside the uterine cavity. Retrograde shed endometrial fragments are presumed to adhere to pelvic structures and grow invasively, thereby creating endometriotic tissue. READ MORE

  7. 20. Genomic clues to secondary injury mechanisms in brain trauma

    Author : Christina von Gertten; Karolinska Institutet; Karolinska Institutet; []
    Keywords : traumatic brain injury; cerebral cortical contusion; weight-drop model; depolarisation; gene expression; nestin; MMP-9; TIMP-1; osteopontin; CD44; hippocalcin; NMDA receptor; microarray; rat;

    Abstract : Traumatic brain injury (TBI) is a heterogenous disease that can lead to persistent disability or death. The immediate mechanical disruption of brain tissue is followed by a phase of secondary brain injury. During this phase TBI challenges clinical interventions due to its complexity. READ MORE