Search for dissertations about: "in vitro bioaccessibility"

Showing result 1 - 5 of 8 swedish dissertations containing the words in vitro bioaccessibility.

  1. 1. Improving vitamin A nutrition in low-income countries. In vitro bioaccessibility of provitamin A carotenoids in biofortified orange-fleshed sweet potato

    Author : Anton Bengtsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; bioaccessibility; β-carotene; biofortification; provitamin A carotenoids; coherent anti-Stokes Raman scattering microscopy; vitamin A deficiency; food processing; orange-fleshed sweet potato; in vitro digestion; Caco-2 cells;

    Abstract : Vitamin A deficiency is a major nutritional disorder in a large number of low-income countries that is caused by an inadequate intake of preformed vitamin A and provitamin A carotenoids in the diet. The objective of the present thesis was to evaluate orange-fleshed sweet potato (OFSP) as a biofortified food source of provitamin A carotenoids with a potential to be included in a diet for alleviating vitamin A deficiency. READ MORE

  2. 2. Metal Particles – Hazard or Risk? Elaboration and Implementation of a Research Strategy from a Surface and Corrosion Perspective

    Author : Klara Midander; Inger Odnevall Wallinder; Sannakaisa Virtanen; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ferro-chromium alloy; metal particles; bioaccessibility; chemical speciation; dermal contact; surface oxide; in-vitro testing; chemical speciation; cu; copper; comet assay; intracellular; ultrafine; in vitro; A549; cytotoxicity; DNA damage; nanoparticles; particle characterization; artificial sweat; nickel release; nickel powder particles; particle loadings; release kinetics; surface area; copper release; powder particles; synthetic body fluids; simulation of interstitial lung conditions; skin contact; metal release; stainless steel; particles; test method; Surface and colloid chemistry; Yt- och kolloidkemi; Analytical chemistry; Analytisk kemi; Spectroscopy; Spektroskopi;

    Abstract : Do metal particles (including particles of pure metals, alloys, metal oxides and compounds) pose a hazard or risk to human health? In the light of this question, this thesis summarizes results from research conducted on metal particles, and describes the elaboration and implementation of an in vitro test methodology to study metal release from particles through corrosion and dissolution processes in synthetic biological media relevant for human exposure through inhalation/ingestion and dermal contact. Bioaccessible metals are defined as the pool of released metals from particles that potentially could be made available for absorption by humans or other organisms. READ MORE

  3. 3. In vitro Bioaccessibility of Carotenes: Influence of microstructure in tomato and carrot as modified by processing

    Author : Cecilia Svelander; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; α-carotene; in vitro bioaccessibility; high-pressure homogenisation; carrot; in vivo bioavailability; Caco-2 cell model; blanching; processing; Lycopene; β-carotene; tomato; microstructure;

    Abstract : Carotenes are a group of fat-soluble pigments in many fruits and vegetables associated with several important biological effects, like protection against the development of some forms of cancer and cardiovascular disease. The carotene bioavailability in plant foods, i.e. READ MORE

  4. 4. Bioaccessibility, corrosion and surface properties of metals, alloys and metallic powder in biological fluids of relevance for occupational and consumer health hazard assessment

    Author : Xuying Wang; Inger Odnevall Wallinder; Yolanda S. Hedberg; Lars Nyborg; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metal and alloy; metal release; synthetic biological fluids; surface oxide; corrosion resistance; hazard assessment; Kemi; Chemistry;

    Abstract : When assessing hazards of metals, alloys, and metal-containing items, the metal release (bioaccessibility) is of high importance. Triggered by increasingly stricter hazard classifications for metals, especially cobalt (Co), and limited knowledge, the aim of this doctoral thesis is to assess correlations between the metal/alloy surface characteristics, corrosion and metal release pattern in different simulated biological fluids relevant to human exposure scenarios (dermal, ingestion and inhalation, Papers I-V). READ MORE

  5. 5. Stainless Steel in Biological Environments – Relation between Material Characteristics, Surface Chemistry and Toxicity

    Author : Yolanda Hedberg; Inger Odnevall Wallinder; Sasha Omanovich; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Triggered by the regulatory need of the industry to demonstrate safe use of their alloy products from an environmental and health perspective, and by the significant lack of metal release data and its correlation to material and surface characteristics for iron- and chromium-based alloys, a highly interdisciplinary in-depth research effort was undertaken to assess the relation between material/surface characteristics and toxicity with main emphasis on stainless steel alloys. This thesis focuses predominantly on studies made on AISI 316L both as massive sheet and as powder particles, but includes also results for other stainless steel grades and reference metals and metal oxides. READ MORE