Search for dissertations about: "in vitro function"

Showing result 1 - 5 of 1235 swedish dissertations containing the words in vitro function.

2. 1. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells : Investigations in vitro and in Reactive Tissues in vivo

   Author : Jakob Karén; Christian Sundberg; Gunilla Westergren-Thorsson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pericyte fibroblast differentiation fibrosis; Biochemistry; Biokemi; Microbiology; Mikrobiologi; Cell biology; Cellbiologi; Medical Biochemistry; Medicinsk biokemi; Cellforskning; Cell Research; Mikrobiologi; Microbiology;

   Abstract : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. READ MORE

4. 2. Regulation of Renal Hyaluronan in Water Handling : Studies in vivo and in vitro

   Author : Sara Stridh; Peter Hansell; Mats Rundgren; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; water balance; fluid handling; diabetes; nephropathy; ACE fetopathy; reabsorption; hyaluronic acid; glycosaminoglycan; GAG; extracellular matrix; mTOR; rapamycin; streptozotocin;

   Abstract : Hyaluronan (HA) is a negatively charged extracellular matrix (ECM) component with water-attracting properties. It is the dominating ECM component in the renal medullary interstitium, where the amount changes in relation to hydration status: it increases during hydration and decreases during dehydration. READ MORE

5. 3. Up-regulation of dopamine D₂ receptors : in vitro and in vivo studies

   Author : Maria Wanderoy; Eliassitet Eriksson; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry; Neurokemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

   Abstract : In the central nervous system (CNS) dopaminergic and dopaminoceptive neurons have the ability to respond to variations in dopamine levels by for example adjusting their dopamine receptor levels. One of the most well known phenomena in this respect is that long-term blockade of D2 receptors with antipsychotic drugs leads to an increase in striatal D2 receptor density of experimental animals as well as of schizophrenic patients as measured in both post-mortem studies and in vivo positron emission tomography studies of brain. READ MORE

6. 4. Dendritic cells in allergy In vitro models for studies of the human immune response

   Author : Kristina Larsson; Institutionen för immunteknologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; vaccine; Th2; transcriptional profiling; T cell; nanosphere; Immunologi; MUTZ-3; microarray; in vitro model; Allergic rhinitis; dendritic cell; serologi;

   Abstract : This thesis, which is based on four original papers, deals with human dendritic cells (DCs) in immunity and allergy. DCs play a key role in the regulation of immune responses by acting as the sentinels of the immune system, specialized in the uptake of a diverse range of antigens. READ MORE

7. 5. Actomyosin in biocomputation

   Author : Aseem Salhotra; Alf Månsson; Henry Hess; Linnéuniversitetet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; biocomputation; molecular motors; 3-SAT; surface chemistry; actomyosin; actin; myosin II; heavy meromyosin; myosin XI; engineered myosin; in vitro motility assay; nanofabrication; alternate computing; network based biocomputation; protein-surface interaction; longevity; prolongation; surface recycling; affinity purification; blocking actin; Bioteknik; Biotechnology; Biokemi; Biochemistry;

   Abstract : There exist complex mathematical problems that are important in real world applications such as weather prediction, molecular modelling, network route optimization and more. In general, such problems are solved using supercomputers with higher computing efficiency but this also consumes high energy along with high production and maintenance cost. READ MORE