Search for dissertations about: "inflammatory bowel diseases"

Showing result 6 - 10 of 99 swedish dissertations containing the words inflammatory bowel diseases.

2. 6. Macrophages in Crohn's Disease: lnnate immune cellular and molecular mechanisms driving intestinal inflammation and fibrosis

   Author : Frida Gorreja; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; macrophages; inflammatory macrophages; tissue-resident macrophages; efferocytosis; innate immunity; myeloid cells; fibroblasts; fibrosis; inflammasomes; Crohn´s disease; inflammatory bowel diseases; digestive diseases; mucosa immunology; intestinal immunity; intestinal inflammation; serum systemic inflammation; microbiota; metabolites;

   Abstract : Macrophages and their interactions with the lamina propria and luminal microenvi-ronment are crucial in the pathogenesis of Crohn´s disease (CD), a chronic inflamma-tory disease with a strong inflammatory innate immune involvement. Therefore, in-terpreting macrophage activity in the intestinal microenvironment may identify treatment targets beneficial for at least a subgroup of patients. READ MORE

4. 7. Fertility in Inflammatory Bowel Disease

   Author : Emma Druvefors; Pär Myrelid; Roland Andersson; Kalle Landerholm; Gunilla Sydsjö; Sonia Friedman; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ulcerative colitis; Crohn’s disease; Fertility; Ileal pouch anal anastomosis; Ileorectal anastomosis;

   Abstract : Inflammatory bowel diseases (IBD) often present in adolescence or early adulthood and is thus frequently diagnosed in men and women in their reproductive age. Previous population-based studies of fertility in patients with IBD are scarce. READ MORE

5. 8. Serological and faecal biomarkers in inflammatory bowel disease

   Author : Karin Amcoff; Jonas Halfvarson; Marie Carlsson; Hans Törnblom; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Crohn s disease; ulcerative colitis; inflammatory bowel disease; faecal calprotectin; antibodies; eosinophils; ECP; EDN;

   Abstract : The inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are relapsing and remitting disorders characterised by chronic inflammation at various sites in the gastrointestinal tract, resulting in diarrhoea and abdominal pain. Neither the aetiology nor the pathophysiology is yet fully understood, and there is currently no cure. READ MORE

6. 9. Bone mineral density in pediatric inflammatory bowel disease

   Author : Susanne Schmidt; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone mineral density; inflammatory bowel disease; children; Crohn s disease; ulcerative colitis; vitamin D; parathyroid hormone; familial resemblance; body composition; growth;

   Abstract : Low bone mineral density (BMD) has been highlighted as a potential problem in children with inflammatory bowel disease (IBD), which is one of the most common chronic childhood diseases in the westernized world. The mechanisms behind reduced BMD in pediatric IBD are still not completely understood, but several factors that influence bone mineralization have been discussed. READ MORE

7. 10. Neuro-immuno-regulation of inflammation in the colonic mucosa : Focus on mast cells and eosinophils in bowel disorders

   Author : Maria Teresa Casado Bedmar; Åsa Keita; Johan D Söderholm; Marie Carlson; Melanie Gareau; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; Eosinophils; Vasoactive intestinal polypeptide; Neuro-immune; Intestinal barrier; Irritable bowel syndrome; Inflammatory bowel diseases; Ussing chamber; Advance image analysis;

   Abstract : Intestinal homeostasis is key to control uptake across the mucosa and protect from harmful substances. Disturbances in the bidirectional communication between the gut and the brain are implicated in irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD), being Crohn’s disease (CD) and ulcerative colitis (UC) the two most common IBD subtypes. READ MORE