Search for dissertations about: "inherited susceptibility"
Showing result 1 - 5 of 45 swedish dissertations containing the words inherited susceptibility.
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1. Neurotoxic Effects of Nicotine During Neonatal Brain Development : Critical Period and Adult Susceptibility
Abstract : This thesis examined neurotoxic effects of nicotine exposure during a defined critical period of neonatal brain development in mice.In our environment there are numerous hazardous contaminants that an individual can be exposed to during its entire lifetime. READ MORE
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2. The Complex Genetics behind Neurodegeneration and Susceptibility to Parkinson’s disease
Abstract : Parkinson’s disease (PD) is the second most common neurodegenerative disorder and affects over 1% of people above the age of 65. This progressive and debilitating disease is usually thought of as a motor disease, with symptoms such as muscle rigidity, slowness of movement, and tremor at rest. READ MORE
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3. Genetic susceptibility to cervical and gastric cancer
Abstract : Cervical and gastric cancer both to a large extent depend on infectious agents. Cervical infection with human papilloma virus increases the risk for cervical cancer substantially, and infection with the bacteria Helicobacter pylori increases the risk for gastric cancer. READ MORE
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4. Identification and characterization of DNA sequence variants associated with multiple myeloma
Abstract : Multiple myeloma (MM) is the second most common hematologic malignancy. The disease is characterized by an uncontrolled growth of malignant plasma cells in the bone marrow, producing a monoclonal immunoglobulin (“M protein”) that can be detected in peripheral blood. READ MORE
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5. Modeling genetic susceptibility to multiple sclerosis
Abstract : The main aim of this thesis was to investigate genetic and environmental factors and their role in the etiology of Multiple Sclerosis (MS) by using comprehensive registry data or novel computationally intense methods. To date, over 100 genes associated with MS have been identified, but how they interact in the risk for the disease is not yet fully understood. READ MORE