Search for dissertations about: "innate immune cells"

Showing result 1 - 5 of 467 swedish dissertations containing the words innate immune cells.

2. 1. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response

   Author : Rada Ellegård; Marie Larsson; Jorma Hinkula; Johan D Söderholm; William Paxton; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

   Abstract : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. READ MORE

4. 2. Functions and memory features of adaptive- and innate immune cells in physiological and inflammatory settings

   Author : Gintare Lasaviciute; Eva Sverremark-Ekström; Silke Appel; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Innate immune memory; Limosilactobacillus reuteri; dendritic cells; lymphocytes; cytokines; immunological memory; intestinal epithelial cells; chemotherapy; bone marrow; secondary lymphoid organs; molekylär biovetenskap; Molecular Bioscience;

   Abstract : The immune system is a complex but well-regulated network which cooperates with the microbiota to maintain optimal homeostasis under physiological settings. A number of factors display the capacity to alter the immune system and thus microbiota crosstalk including host genetics, diet, environmental influences and drugs such as antibiotics or chemotherapeutic agents. READ MORE

5. 3. Plasmodium falciparum-mediated modulation of innate immune cells: responses and regulation

   Author : Ioana Bujila; Ann-Kristin Östlund Farrants; Marita Troye-Blomberg; Artur Scherf; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plasmodium falciparum; hemozoin; innate immune cells; sympatric ethnic groups; immunologi; Immunology;

   Abstract : Plasmodium falciparum (P. falciparum) infection modulates the response of innate immune cells. The aim of this work was to study the impact of P. falciparum infection and P. READ MORE

6. 4. Dendritic cells in cancer immunotherapy

   Author : Karin Gustafsson; Göteborgs universitet; []
   Keywords : vaccines; dendritic cells; αDC1; PGE2DC; natural killer cells; T cells;

   Abstract : Dendritic cells (DCs) play a central role in the initiation and regulation of innate and adaptive immune responses and have increasingly been applied as vaccines for cancer patients. Ex vivo generation and antigen loading of monocyte-derived DCs allows a controlled maturation, with the aim of imprinting different DC functions that are essential for their subsequent induction of a T cell-mediated anti-tumor response. READ MORE

7. 5. Regulatory aspects of innate immune responses

   Author : Ahmed El Marghani; Per-Erik Olsson; Peter Kjellén; Muhammad Zafarullah; Örebro universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Innate immunity; TOM1L1; inflammatory responses; Biology; Biologi;

   Abstract : Activation of innate immunity is regulated by a variety of signaling molecules within the immune cells. The present thesis was aimed to improve our understanding of innate signaling mechanism and their possible use as bio-indicators of exposure and disease. READ MORE