Search for dissertations about: "institutionen för medicinska vetenskaper"

Showing result 1 - 5 of 839 swedish dissertations containing the words institutionen för medicinska vetenskaper.

  2. 1. Dysregulated mucosal immune responses in microscopic colitis patients

    Author : Sezin Günaltay; Elisabeth Hultgren-Hörnquist; Olof Hultgren; Nils Nyhlin; Allan Mowat; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microscopic colitis; collagenous colitis; lymphocytic colitis; TLR; chemokine; chemokine receptor; IL-37; TCR; Immunologi; Immunology; Biomedicin; Biomedicine;

    Abstract : Microscopic colitis (MC), comprising collagenous colitis (CC) and lymphocytic colitis (LC) is a common cause of chronic watery diarrhea. The diagnosis relies on typical histopathological changes observed upon microscopic examination. READ MORE

  4. 2. Improving the Quality and Safety of Drug Use in Hospitalized Elderly : Assessing the Effects of Clinical Pharmacist Interventions and Identifying Patients at Risk of Drug-related Morbidity and Mortality

    Author : Anna Alassaad; Håkan Melhus; Margareta Hammarlund-Udenaes; Johan Sundström; Claes Mörlin; Lene Juel Kjeldsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adverse drug events; inappropriate prescribing; medication errors; polypharmacy; medication reconciliation; medication review; patient drug counseling; multi-dose dispensed drugs; risk-estimation; multiprofessional collaboration; prediction model; quality measure; rehospitalization;

    Abstract : Older people admitted to hospital are at high risk of rehospitalization and medication errors. We have demonstrated, in a randomized controlled trial, that a clinical pharmacist intervention reduces the incidence of revisits to hospital for patients aged 80 years or older admitted to an acute internal medicine ward. READ MORE

  5. 3. Interactions between Streptococcus pyogenes and the human immune defence

    Author : Maria E Nilsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M protein; Streptococcus pyogenes; Streptolysin O; The complement system; Neutrophils; Biomedical sciences; Biomedicinska vetenskaper; General biomedical sciences; Biomedicinska vetenskaper allmänt ; Microbiology; transplantation; Immunology; serology; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; Immunologi; serologi; Infections; Infektioner; Clinical biology; Klinisk biologi; bacteriology;

    Abstract : Streptococcus pyogenes is an important human pathogen frequently colonizing the throat and skin of humans. To facilitate colonization and spread and to avoid the host immune defence, streptococci are endowed with a variety of virulence factors, two of which are investigated in this thesis namely streptolysin O (SLO) and M protein. READ MORE

  6. 4. Physiology and Pharmacology of GABAA receptors: The Brakes in the Brain

    Author : Catarina Lindquist; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; Fysiologi; Ion channels; GABA; Inhibition;

    Abstract : Inhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). READ MORE

  7. 5. HAMLET - In vivo effects and mechanisms of tumor-cell death

    Author : Lotta Gustafsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Biomedical sciences; proteasome stress; HAMLET; human milk; tumor-cell death; clinical trial; rat xenograft model; skin papilloma; glioblastoma;

    Abstract : HAMLET (human alpha-lactalbumin made lethal to tumor cells), a molecular complex derived from human milk, is an interesting new tool in cancer research since it induces programmed cell death in tumor cells while leaving normal, differentiated cells unharmed. The in vivo effects of HAMLET were studied in a rat xenograft model of human glioblastoma. READ MORE