Search for dissertations about: "insulin sensitivity and adipogenesis"
Found 5 swedish dissertations containing the words insulin sensitivity and adipogenesis.
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1. Assessment and Treatment of Impaired Insulin- Secretion and Action in Type 2 Diabetes
Abstract : Type 2 diabetes (T2D) is a disease characterised by varying degrees of defect in insulin secretion and insulin sensitivity and associated with increased morbidity and mortality. Optimal glycaemic control reduces the progression of diabetic complications. READ MORE
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2. Angiogenesis modulates obesity and insulin sensitivity
Abstract : Both white and brown fat are highly vascularized tissues and vascular functions in adipose tissues remain largely unknown. In this thesis work, we aimed to study blood vessels in modulation of adipose tissue functions under physiological conditions. READ MORE
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3. Genetics of type 2 diabetes and the metabolic syndrome
Abstract : Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. READ MORE
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4. Molecular characterization of insulin resistance in the adipose tissue and the effects of thiazolidinediones
Abstract : Type 2 diabetes is the most common metabolic disorder today and has reached epidemic proportions in many contries. Insulin resistance plays a central role in the pathogenesis of Type 2 diabetes and can be present for a decade or more before onset of the disease. READ MORE
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5. The role of thyroid stimulating hormone receptor and novel candidate genes FAM13a and POM121c in adipocyte dysfunction
Abstract : This thesis aimed to investigate the role of thyroid stimulating hormone receptors (TSHRs) in adipose tissue (AT) and their role in AT dysfunction and obesity-related metabolic complications. Furthermore, we aimed to functionally evaluate novel candidate genes associated with insulin resistance, a marker of dysfunctional adipose tissue. READ MORE