Search for dissertations about: "insulin thyroid"
Showing result 1 - 5 of 29 swedish dissertations containing the words insulin thyroid.
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1. Assessment and Treatment of Impaired Insulin- Secretion and Action in Type 2 Diabetes
Abstract : Type 2 diabetes (T2D) is a disease characterised by varying degrees of defect in insulin secretion and insulin sensitivity and associated with increased morbidity and mortality. Optimal glycaemic control reduces the progression of diabetic complications. READ MORE
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2. Life without thyroid hormone receptors
Abstract : Thyroid hormone (TH) has many important functions during development and in the adult individual. It reaches its target cells via the blood system and binds its receptor (TR) located within the cell nucleus where the receptor regulates target genes. This hormone-mediated gene regulation is a finely tuned interplay of numerous parameters. READ MORE
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3. The endocrine system in the progression of mild cognitive impairment to dementia
Abstract : Background and aims: Endocrine alterations have been related to cognitive decline, but the role of hormones may vary along the progression to manifest dementia. The overall aim of this thesis was to assess whether thyroid hormones (THs) and insulin-like growth factor-I (IGF-I) are dysregulated around the onset of Alzheimer’s disease (AD) and vascular dementia (VaD). READ MORE
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4. Aspects of beta cell and thyroid autoimmunity in children
Abstract : The two most common autoimmune endocrine diseases in children are autoimmune thyroiditis (AIT) and Type 1 (insulin-dependent) diabetes mellitus (IDDM). Autoantibodies (ab) can be found several years before clinical diagnosis in both diseases. READ MORE
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5. Genetic and functional studies on the thyroid hormone axis
Abstract : This thesis has two main parts. The first is based on the first three papers with a focus on understanding the etiology and pathogenesis of thyroid malfunction and its effects on different organs. READ MORE