Search for dissertations about: "interleukin 3"

Showing result 1 - 5 of 251 swedish dissertations containing the words interleukin 3.

  2. 1. Effects of Interleukin-4 and Interleukin-13 on Bone

    Author : Carl-Johan Silfverswärd; Olle Nilsson; Östen Ljunggren; Kenneth Jonsson; Li Felländer-Tsai; Uppsala universitet; []
    Keywords : Medicine; Bone; Osteoblasts; Interleukin-4; Interleukin-13; Knockout; Medicin;

    Abstract : Cytokines play important roles in bone metabolism, participating in the complex interplay necessary for normal bone formation and turnover. The aim of the present thesis was to investigate the effects of two anti-inflammatory cytokines, interleukin-4 (IL-4) and interleukin-13 (IL-13) on bone. READ MORE

  4. 2. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

    Author : Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

    Abstract : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. READ MORE

  5. 3. Alternative splicing of interleukin-7

    Author : Nalini Kumar Vudattu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alternative splicing of pre-mRNA is the primary source of creating proteome diversity in humans; it is therefore highly relevant to disease and therapy. Alternative splicing has been described for many cytokines and these splice variants appear to function as either agonists or as antagonists of the wildtype cytokine. READ MORE

  6. 4. The Human Endometrium : Studies on Angiogenesis and Endometriosis

    Author : Christian Moberg; Matts Olovsson; Anneli Stavreus-Evers; Lalit Kumar Parameswaran Grace; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endometrium; angiogenesis; endothelial cell; endometriosis; receptivity; implantation; oestrogen receptor; progesterone receptor; crystallin; interleukin; vasoactive intestinal peptide; peritoneal fluid; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Angiogenesis is thought to play a pivotal role in the cycling endometrium. Coordinated by oestrogen and progesterone, endometrial blood vessel development is primarily mediated by vascular endothelial growth factor-A (VEGF-A), which promotes endothelial cell (EC) proliferation and protects ECs from induced apoptosis. READ MORE

  7. 5. Affibody molecules for proteomic and therapeutic applications

    Author : Caroline Grönwall; Stefan Ståhl; Lena Jendeberg; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Affibody; protein engineering; phage display; amyloid beta peptide; transferrin; CD25; IL-2 receptor; proteomics; Bioengineering; Bioteknik;

    Abstract : This thesis describes generation and characterization of Affibody molecules with future applications in proteomics research, protein structure determinations, therapeutic treatment of disease and medical imaging for in vivo diagnostics. Affibody molecules are engineered affinity proteins developed by combinatorial protein engineering from the 58-residue protein A-derived Z domain scaffold. READ MORE