Search for dissertations about: "ischaemia-reperfusion"

Showing result 1 - 5 of 16 swedish dissertations containing the word ischaemia-reperfusion.

  2. 1. Effect of Ischaemia-Reperfusion on Rabbit Kidney and Human Brain

    Author : Jagdish Shivlal Gondalia; Göteborgs universitet; []
    Keywords : Free radicals; ischaemia-reperfusion; cell bioenergetics; NMR; ESR; carotid artery stenosis; endarterectomy; allopurinol; acetylcysteine; MMP-1; ICAM-1; MCP-9; oxLDL;

    Abstract : Free radicals are produced in various organs at ischaemia-reperfusion. The final stage in radical damage is lipid peroxidation. We have demonstrated previously that a lipid-soluble antioxidant improves restoration of bioenergetics in rabbit kidneys after ischaemia, as reflected in 31P spectrometry. READ MORE

  4. 2. Attenuation of Oxidative Stress, Inflammation and Colorectal Oncogenesis by Food Constituents: Ischaemia/Reperfusion Injury and Induced Colitis in Rodents

    Author : Åsa Håkansson; Avdelningen för livsmedel och läkemedel; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; Ischaemia Reperfusion; Rose hips; Colitis; Probiotics; Inflammation; Blueberry;

    Abstract : The enteric microbiota is increasingly implicated as a central factor in the development of intestinal inflammation in humans and experimental animals, and the intestinal environment is considered important in both colorectal cancer development and modulation of mucosal immunity. Diet-induced changes in the different populations of the intestinal microbiota can be achieved by use of probiotic bacteria, dietary fibre and berries rich in phenolic compounds. READ MORE

  5. 3. Monitoring and prevention of ischaemia-reperfusion injury in liver transplantation : experimental and clinical studies

    Author : Grzegorz Nowak; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Liver function after transplantation is determined not only by the quality of the donor organ or recipient related factors, but also by factors associated with organ preservation. During preservation, the liver graft is exposed to ischaemia and reperfusion with subsequent injury to the transplanted liver. READ MORE

  6. 4. Cardioprotective mechanisms by inhibition of the HMG-CoA reductase pathway and stimulation of peroxisome proliferator-activated receptors in myocardial ischaemia-reperfusion

    Author : Aliaksandr Bulhak; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Endothelial function; endothelin-1; geranylgeranyl pyrophosphate; HMG-CoA reductase; infarct size; ischaemiareperfusion injury; myeloperoxidase; myocardium; nitric oxide; nitric oxide synthase; peroxisome proliferator-activated receptor-alpha; -gamma; PPAR-alpha; -gamma-ligands; RhoA; statins.;

    Abstract : Acute myocardial ischaemia causes metabolic changes and results in a rapid decrease in the energy available to the cell. This leads to cell injury that, depending on the length of the ischaemic time, is reversible or irreversible. READ MORE

  7. 5. The role of endothelin during myocardial ischaemia and reperfusion : pathophysiological mechanisms and interactions with nitric oxide

    Author : Adrian T Gonon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ischaemia; reperfusion injury; myocardium; infarct size; endothelium; endothelin; endothelin receptor; nitric oxide; nitric oxide synthase; polymorphonuclear leukocytes; myeloperoxidase; pig; rat;

    Abstract : Acute myocardial infarction followed by reperfusion results in accelerated necrosis of irreversibly injured myocytes as well as induction of lethal injury to reversibly injured cells. Polymorphonuclear leukocytes (PMNs) are major participants in the reperfusion-initiated inflammation. READ MORE