Search for dissertations about: "leptin body weight"

Showing result 1 - 5 of 44 swedish dissertations containing the words leptin body weight.

  2. 1. Leptin : a risk marker for cardiovascular disease

    Author : Stefan Söderberg; Ulf de Faire; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; leptin; testosterone; dysfibrinolysis; hyperinsulinemia; insulin resistance syndrome; menopause; cardiovascular disease; MONICA; epidemiology;

    Abstract : A major cause of morbidity and early death in the Western societies is cardiovascular disease (CVD) secondary to atherosclerotic disease. Metabolic aberrations have been linked to CVD. READ MORE

  4. 2. Regulation of Leptin by Sexual Maturation and Energy Status in Male Atlantic Salmon (Salmo salar L.) Parr

    Author : Susanne Trombley; Monika Schmitz; Sylvie Dufour; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Leptin; leptin receptor; Atlantic salmon; Salmo salar; sexual maturation; puberty; energy balance; hepatocytes; sex steriods; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Abstract : Leptin is a peripheral adiposity signal and a key hormone in energy balance regulation in mammals, acting as a link between nutritional status and the endocrine reproductive axis. If this is also the role of leptin in fish is not fully understood. READ MORE

  5. 3. Genes implicated in the development of obesity and obesity-related disease

    Author : Kajsa Lindell; Göteborgs universitet; []
    Keywords : obesity; adipose tissue; hypothalamus; leptin; leptin receptor; 5 untranslated region; hypertension; angiotensinogen; DNA microarray;

    Abstract : Obesity is a major health problem because of its dramatic increase in prevalence and the association of obesity with type 2 diabetes, coronary heart disease, hypertension and stroke. Although mutations in certain genes have been shown to cause obesity, the molecular mechanisms underlying obesity and obesity-related disease are still largely unknown. READ MORE

  6. 4. Insulin-like Growth Factor-I (IGF-I) and Interleukin-6 (IL-6) regulate body fat

    Author : Kristina Wallenius; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; insulin-like growth factor I IGF-I ; interleukin-6 IL-6 ; growth hormone GH ; GH releasing factor GHRF ; GH secretagogue GHS ; receptor; leptin; insulin; glucose; intracerebroventricular ICV ; dual-energy X-ray absorptiometry DXA ; indirect calorimetry.;

    Abstract : The aim of this thesis was to investigate the role of insulin-like growth factor-I (IGF-I) and interleukin-6 (IL-6) in the regulation of metabolism and body fat mass. Circulating IGF-I is mainly liver derived, while a large part of circulating IL-6 is produced by adipose tissue. READ MORE

  7. 5. Alterations in peripheral glucocorticoid metabolism : effects of weight changes

    Author : Kotryna Simonyté; Cecilia Mattsson; Bo Angelin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11ß Hydroxysteroid dehydrogenase 1; obesity; glucocorticoids; cortisol; phosphoenolpyruvate carboxykinase; adipose tissue; liver; Endocrinology; Endokrinologi; medicin; Medicine;

    Abstract : Background: An important role has been suggested for tissue-specific glucocorticoid metabolism in the development of obesity and its complications. 11ß hydroxysteroid dehydrogenase 1 (11ßHSD1) is an enzyme that catalyzes the interconversion of biologically inactive cortisone to active cortisol, thereby regulating its access to glucocorticoid receptors in target tissues. READ MORE