Search for dissertations about: "leptin"

Showing result 21 - 25 of 143 swedish dissertations containing the word leptin.

  1. 21. Polycystic ovary syndrome : A study on factors of potential impact on body fat and carbohydrate metabolism

    Author : Gianluca Gennarelli; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; polycystic ovary syndrome; androgens; insulin; insulin resistance; body fat distribution; hypoglycaemia; adrenal; cortisol; ACTH; leptin; gestational diabetes mellitus; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; Obstetrics and Gynaecology; obstetrik och gynekologi;

    Abstract : The aim of the present thesis was to investigate some factors underlying the metabolic, anthropometric, and endocrine abnormalities of women with the polycystic ovary syndrome (PCOS).An iv insulin tolerance test (0.15 IU bolus) showed substantially preserved glucose counterregulation in women with PCOS (n=18). READ MORE

  2. 22. Psychiatric and metabolic disturbances in experimental models of Huntington’s disease

    Author : Sofia Hult Lundh; Translationell neuroendokrinologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington’s disease; huntingtin; hypothalamus; depression; anxiety; metabolism; neuroendocrinology; mouse models; BACHD; rAAV vectors; leptin;

    Abstract : Non-motor symptoms and signs such as metabolic and psychiatric disturbances have been reported to occur early in Huntington’s disease (HD), a fatal neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. However, there is a lack of understanding of the underlying neurobiological mechanisms responsible for the early non-motor features. READ MORE

  3. 23. The Role of Gut Dysfunction and Nutritional Factors in Liver Cirrhosis

    Author : Evangelos Kalaitzakis; Göteborgs universitet; []
    Keywords : liver cirrhosis; malnutrition; gastrointestinal symptoms; health-related quality of life; food intake; energy expenditure; gastric accommodation; gastric barostat; insulin resistance; leptin; ghrelin; intestinal permeability;

    Abstract : Malnutrition is a common finding in patients with liver cirrhosis. Malnutrition has been shown to be associated with increased morbidity and mortality. Its pathogenesis remains unclear but both poor dietary intake and increased energy expenditure have been reported. Spontaneous bacterial peritonitis is an important clinical problem in cirrhotics. READ MORE

  4. 24. Barnfetma och Metabola Syndromet hos förskolebarn - tidiga faktorer och identifiering av riskindivider från ett longitudinellt perspektiv : Childhood Obesity and Metabolic Syndrome in Preschool Children - Early markers and identification of individuals at increased risk in a longitudinal perspective

    Author : Emma Kjellberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adiponectin; childhood obesity; insulin resistance; leptin; metabolic syndrome; n-6 fatty acids; Subcutaneous adipose tissue; Visceral adipose tissue; waist circumference;

    Abstract : Background: Overweight and obesity have increased worldwide and affect children at ever younger ages, resulting in cardiovascular disease and type 2 diabetes even in adolescents. This illustrates the importance of identifying children at risk at an early stage. Aim: To study metabolic health in preschool children. READ MORE

  5. 25. Milk Genomics – Impact of Genetic Polymorphism on Bovine Milk Composition and Processability

    Author : Maria Glantz; Livsmedelsteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; milk genomics; bovine milk; milk composition; technological properties; processability; cheese; quantitative genetic evaluation; single gene effect; genomic selection; genetic polymorphism; leptin; direct genomic value;

    Abstract : Milk genomics is a new area of research that explores the relations between cow genetics and milk characteristics. Identifying the genes controlling compositional and technological traits of milk will give opportunities to select cows for targeted milk production. In this thesis, the impact of different genetic approaches, i.e. READ MORE