Search for dissertations about: "lipid accumulation"

Showing result 1 - 5 of 190 swedish dissertations containing the words lipid accumulation.

  2. 1. Cardiac lipid storage and metabolism following myocardial ischemia

    Author : Christina Drevinge; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipid accumulation; Myocardial Ischemia; Lipid droplets; Perilipin2; Perilipin5;

    Abstract : Myocardial ischemia is associated with cellular- and metabolic adjustments within the heart, including accumulation of lipids. Myocardial lipids are stored in cytosolic droplets, consisting of a core of neutral lipids surrounded by a complex surface containing proteins, such as perilipins. READ MORE

  4. 2. α-synuclein interactions with lipid membranes

    Author : Katarzyna Makasewicz; NanoLund: Centre for Nanoscience; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; alpha-Synuclein; lipid membranes; protein-lipid interactions; binding cooperativity; membrane remodeling; protei-lipid co-aggregation;

    Abstract : α-synuclein is an intrinsically disordered protein implicated in synaptic vesicle trafficking at the synapse. Accumulation of α-synuclein in the form of amyloid deposits coincides with the loss of dopaminergic neurons in Parkinsons disease. READ MORE

  5. 3. Mechanisms for and consequences of cellular lipid accumulation - Role of the Very Low Density Lipoprotein (VLDL) receptor

    Author : Jeanna Perman; Göteborgs universitet; []
    Keywords : very low density lipoprotein receptor; lipid accumulation;

    Abstract : Lipid accumulation in non adipose tissue is associated with various cases of tissue dysfunction and tissue failure. Reduced availability of oxygen is known to cause intracellular lipid accumulation in cardiomyocytes as well as in hearts. READ MORE

  6. 4. Cardiac lipids and their role in the diseased heart

    Author : Ismena Mardani; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular disease; Lipid droplets; Perilipins; Lipid accumulation; Metabolism; GlcCer;

    Abstract : Lipids play an essential role within the heart as they are involved in energy storage, membrane stability and signaling. Changes in cardiac lipid composition and utilization may thus have profound effects on cardiac function. Importantly, the diseased heart is associated with intracellular metabolic abnormalities, including accumulation of lipids. READ MORE

  7. 5. Engineering Lipid Metabolism for Production of Oleochemicals in Saccharomyces cerevisiae

    Author : Paulo Teixeira; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; oleochemicals; lipid homeostasis; Saccharomyces cerevisiae< i>; lipid metabolism;

    Abstract : Oleochemicals are chemicals usually derived from plant oils or animal fat. Large use of plant oil derivatives as replacements for petroleum-derived chemicals brings sustainability issues from extensive cultivation of oil plants in restricted regions. READ MORE