Search for dissertations about: "lipid accumulation"
Showing result 21 - 25 of 189 swedish dissertations containing the words lipid accumulation.
-
21. Effects of lipid oxidation on transcriptional regulation and cell death
Abstract : Elevated levels of low density lipoprotein (LDL) in plasma are associated with an increased risk for atherosclerosis. Excessive accumulation of lipoproteins and lipids in the vascular wall is thought to lead to the development of advanced atherosclerotic lesions prone to rupture. READ MORE
-
22. Early perturbations in lipid metabolism in insulin resistance
Abstract : Subjects with the Metabolic Syndrome with or without type 2 diabetes are at excess risk for developing cardiovascular disease. The mechanisms are still not completely understood. Resistance to insulin-stimulated glucose uptake is associated with several metabolic and hemostatic risk factors for cardiovascular disease. READ MORE
-
23. Intracellular lipids and inflammatory activity in macrophage foam cells
Abstract : Cardiovascular disease (CVD) is characterized by lipid accumulation and inflammation in arteries. The disease starts early in life with migration of monocytes into the arterial wall where they engulf entrapped lipoproteins and become macrophage foam cell. READ MORE
-
24. Prion-infection and Cellular Signaling : Influence of scrapie-infection on lipid raft-associated proteins
Abstract : Prion diseases are a group of fatal neurodegenerative diseases affecting almost all mammals including humans. The diseases are caused by formation of the misfolded isoform of the cellular prion protein (PrPC) to the disease causing PrPSc. READ MORE
-
25. Adipose tissue inflammation, hepatic fat accumulation and insulin resistance
Abstract : Insulin resistance is the central feature of a variety of metabolic disorders, such as type 2 diabetes and the metabolic syndrome. The incidence of these disorders, often together with obesity, is currently increasing throughout the world. READ MORE