Search for dissertations about: "lipopolysaccharide LPS"

Showing result 1 - 5 of 152 swedish dissertations containing the words lipopolysaccharide LPS.

2. 1. Biomolecules at Interfaces -Studied by Surface and Solution Techniques

   Author : Anna Bergstrand; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; LDL; sepsis; PEG; LPS; lipopolysaccharide; QCM-D; SPR;

   Abstract : The interfacial behaviour of biomolecules in general and proteins in particular is interesting from a biochemical point of view since proteins are involved in processes such as complement activation, blood coagulation and atherosclerotic plaque formation, but also in the context of biomedical applications such as solid-phase diagnostics, therapeutic aphaeresis and biosensors. The objective of this thesis is to study biomolecular interactions using surface sensitive biosensor techniques such as surface plasmon resonance, SPR, in combination with bulk techniques. READ MORE

4. 2. Uptake and fate of pathogenic microbes in the blue mussel, Mytilus edulis

   Author : Bodil Hernroth; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mytilus edulis; bivalve; immune response; lipopolysaccharide; LPS; antimicrobial peptide; gamma camera; radiolabelling; Salmonella typhimurium; sanitary safety; public health;

   Abstract : Bivalves, like the blue mussel Mytilus edulis, are filter-feeders and can therefore accumulate high numbers of microbes from the surrounding water. These shellfish are considered the main risk for bringing pathogens from domestic outlets in the sea, back to the community. READ MORE

5. 3. The role of bacterial endotoxin in the immature brain

   Author : Saskia Eklind; Göteborgs universitet; []
   Keywords : lipopolysaccharide; hypoxia-ischemia; immature; temperature; cerebral blood flow; blood glucose; inflammation; apoptosis; microarray; preconditioning;

   Abstract : Aim: Epidemiological evidence suggests that infections may increase the vulnerability of the immature brain to further insults. The aim of this thesis was to investigate the role of bacterial endotoxin (lipopolysaccharide, LPS) on hypoxic-ischemic (HI) injury in the immature rat brain, and to evaluate possible underlying mechanisms of increased sensitivity. READ MORE

6. 4. Vascular actions of antimicrobial peptides

   Author : Cristina Ciornei; Sektion II; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; vascular smooth muscle; sepsis; nitric oxide; human antimicrobial peptide LL-37; Antimicrobial peptides; lipopolysaccharide; bactericidal permeability-increasing protein;

   Abstract : The present thesis focuses on the vascular effects of antimicrobial peptides especially mechanisms involving the vasodilator nitric oxide (NO), which is released from the blood vessel wall during inflammatory conditions such as sepsis. Bacterial lipopolysaccharide stimulates the expression of nitric oxide synthase (iNOS), which increases the NO production in vascular tissues or cultured vascular smooth muscle cells (VSMC). READ MORE

7. 5. Amphiphilic Peptide Interactions with Complex Biological Membranes : Effect of peptide properties on antimicrobial and anti-inflammatory effects

   Author : Shalini Singh; Martin Malmsten; Per Hansson; Debora Berti; Uppsala universitet; []
   Keywords : LPS; Antimicrobial; Peptide; Inflammation; Infections; Liposome; Binding; PEG; Farmaceutisk fysikalisk kemi; Pharmaceutical Physical Chemistry;

   Abstract : With increasing problem of resistance development in bacteria against conventional antibiotics, as well as problems associated with diseases either triggered or enhanced by infection, there is an urgent need to identify new types of effective therapeutics for the treatment of infectious diseases and its consequences. Antimicrobial and anti-inflammatory peptides have attracted considerable interest as potential new antibiotics in this context. READ MORE