Advanced search

Showing result 1 - 5 of 500 swedish dissertations matching the above criteria.

2. 1. Adsorption Studies with Liquid Chromatography : Experimental Preparations for Thorough Determination of Adsorption Data

   Author : Lena Edström; Jonas Bergquist; Lars Hagel; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid chromatography; HPLC; UHPLC; Reversed phase; Preparative chromatography; Adsorption isotherm; Injection profile; Sample pH; pH stable conditions; Peak deformation; Band distortion; Overloaded band; Chiral preparative chromatography; Analytical Chemistry; Analytisk kemi;

   Abstract : Analytical chemistry is a field with a vast variety of applications. A robust companion in the field is liquid chromatography, the method used in this thesis, which is an established workhorse and a versatile tool in many different disciplines. READ MORE

4. 2. Characterizing Chromatography Media : NMR-based Approaches

   Author : Fredrik Elwinger; István Furó; Stéphane Viel; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; chromatography; nuclear magnetic resonance; NMR; self-diffusion; magic-angle spinning; quantitative; distribution coefficient; pore size; Kemi; Chemistry;

   Abstract : Liquid chromatography is an essential technique in manufacturing biopharmaceuticals where it is used on all scales from analytical applications in R&D to full-scale production. In chromatography the target molecule, typically a protein, is separated and purified from other components and contaminants. READ MORE

5. 3. Hydrophilic Separation Materials for Liquid Chromatography

   Author : Petrus Hemström; Knut Irgum; Peter Schoenmakers; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chromatography; HILIC; Hydrophilic; Stationary phase; Chemistry; Kemi;

   Abstract : The main focus of this thesis is on hydrophilic interaction chromatography (HILIC) and the preparation of stationary phases for HILIC. The mechanism of HILIC is also discussed; a large part of the discussion has been adapted from a review written by me and professor Irgum for the Journal of Separation Science (ref 34). READ MORE

6. 4. Liquid Chromatography Coupled to Mass Spectrometry : Implementation of Chemometric Optimization and Selected Applications

   Author : My Moberg; Jonas Bergquist; Karin E. Markides; Dan Bylund; Douglas B. Kell; Uppsala universitet; []
   Keywords : Analytical chemistry; liquid chromatography; mass spectrometry; tandem mass spectrometry; electrospray ionization; inductively coupled plasma; chemometrics; optimization; multivariate data analysis; design of experiments; response surface model; siderophore; azathioprine; peptide; Analytisk kemi;

   Abstract : Liquid chromatography (LC) coupled to mass spectrometry (MS) offers highly selective and sensitive analysis of a wide variety of compounds. However, the use of hyphenated experimental set-ups implies that many parameters may have an effect on the studied response. READ MORE

7. 5. Development and improvement of methods for characterization of HPLC stationary phases

   Author : Torgny Undin; Torgny Fornstedt; Jörgen Samuelsson; Anders Törncrona; Johan Ekeroth; Douglas Westerlund; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Adsorption isotherms; Elution by characteristic points; Inflection points; Single component adsorption; Elution by characteristic points method; Slope data; ECP-slope method; Adsorption; Adsorption energy distribution; Adsorption isotherms; AED; Characterization of adsorption processes; Chromatographic analysis; Chromatography; Hydrophobic-subtraction method HSM ; Hydrophobicity; Linear methods; Linear Models; Liquid chromatography; metoprolol; Non-linear methods; Nonlinear methods; phenol; priority journal; propranolol; Retention mechanism; reversed phase liquid chromatography; Solvation; Subtraction method; Thermodynamics; Chemistry with specialization in Surface Biotechnology; Kemi med inriktning mot ytbioteknik;

   Abstract : High Performance Liquid Chromatography (HPLC) is a widely used tech-nique both for detecting and purifying substances in academy and in the industry. In order to facilitate the use of, and knowledge in HPLC, character-ization of stationary phases is of utmost importance. READ MORE