Search for dissertations about: "liver analysis"

Showing result 1 - 5 of 369 swedish dissertations containing the words liver analysis.

  2. 1. Inductively Coupled Plasma Atomic Emission Spectrometry : Exploring the Limits of Different Sample Preparation Strategies

    Author : Barbro Kollander; Jean Pettersson; Marit Andersson; Jonas Bergquist; Grethe Wibetoe; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; multi element analysis; trace element; ICP-AES; inductively coupled plasma atomic emission spectromtery; water analysis; liver analysis; non digested samples; medical samples; biological samples; samples from biopsies and autopsies; mice organ; fast analysis; internal standard; preconcentration; matrix elimination; Cu; Zn; Mn; Co; Pb; Cd; Mg; Ca; Fe; Ni; Cr; S; P; K; Al; Analytical chemistry; Analytisk kemi; Analytical Chemistry; Analytisk kemi;

    Abstract : This thesis describes two different sample preparation strategies for inductively coupled plasma atomic emission spectrometry (ICP-AES), and their ability regarding multi element quantification in complex samples. Sensitivity, repeatability, reproducibility and accuracy were investigated. READ MORE

  4. 2. Quantitative Evaluation of Contrast Agent Dynamics in Liver MRI

    Author : Nils Dahlström; Örjan Smedby; Torkel Brismar; Anders Ynnerman; Carsten Thomsen; Linköpings universitet; []
    Keywords : Liver; spleen; hepatobiliary system; liver function; MRI; DCE-MRI; Gd-EOBDTPA; Gd-BOPTA; pharmacokinetic; hepatocyte; relaxivity.; MEDICINE; MEDICIN;

    Abstract : The studies presented here evaluate the biliary, parenchymal and vascular enhancement effects of two T1-shortening liver-specific contrast agents, Gd-BOPTA and Gd-EOB-DTPA, in Magnetic Resonance Imaging (MRI) of healthy subjects and of patients.Ten healthy volunteers were examined with both contrast agents in a 1. READ MORE

  5. 3. Proteomic and Functional Analysis of In Vitro Systems for Studies of Drug Disposition in the Human Small Intestine and Liver

    Author : Magnus Ölander; Per Artursson; Pär Matsson; Edward L. LeCluyse; Volker Lauschke; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; drug disposition; ADMET; drug transport; drug metabolism; hepatotoxicity; small intestine; liver; caco-2; human hepatocytes; cryopreservation; apoptosis; liver zonation; non-parenchymal cells; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : To reach the bloodstream, an orally administered drug must be absorbed through the small intestine and avoid extensive clearance in the liver. Estimating these parameters in vitro is therefore important in drug discovery and development. READ MORE

  6. 4. Liver Resection for Colorectal Cancer Metastases. Prognostic Factors and Interventions Affecting Outcome

    Author : LIDEWIJ SPELT; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; artificial neural networks; chemotherapy; colorectal cancer; liver metastasis; liver resection; portal vein embolisation; prognostic factors; survival analysis;

    Abstract : Background: With a yearly incidence of 56 per 100,000 inhabitants, colorectal cancer (CRC) is one of the most common malignancies in the Western world, representing the third leading cause of cancer-related mortality. Within three years after the diagnosis of CRC, 29% of patients will have developed liver metastases. READ MORE

  7. 5. Colorectal Cancer Liver Metastases : Effects of Chemotherapy on Liver Parenchyma and Resections

    Author : Jozef Urdzik; Agneta Norén; Per Hellman; James O Garden; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Current multimodal treatment of colorectal cancer liver metastasis often combines liver resections with preoperative chemotherapy with a 5-year survival of 40-50%. Preoperative chemotherapy includes conversion of initially non-resectable situation and control of micrometastatic disease. READ MORE