Search for dissertations about: "liver disease"

Showing result 21 - 25 of 489 swedish dissertations containing the words liver disease.

  2. 21. Understanding the genetic architecture of fatty liver disease

    Author : Jamialahmadi Oveis; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-alcoholic fatty liver disease; Polygenic risk score; Genomewide association studies; Mendelian Randomization;

    Abstract : Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease, ranging from simple steatosis to more severe conditions, namely non-alcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). NAFLD has a strong genetic component, and its heritability depends on environmental factors and ethnicity. READ MORE

  4. 22. Coagulation in children with liver disease

    Author : Maria Magnusson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : FVIIa;

    Abstract : About 100 new children in Sweden require care at a tertiary pediatric ward each year for severe liver disease. These children are at risk for both severe gastrointestinal bleeding, which may be life threatening, and intra- or extrahepatic thrombosis. READ MORE

  5. 23. Non-Invasive Characterization of Liver Disease : By Multimodal Quantitative Magnetic Resonance

    Author : Markus Karlsson; Peter Lundberg; Gunnar Cedersund; Nils Dahlström; Stergios Kechagias; Steven Sourbron; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : There is a large and unmet need for diagnostic tool that can be used to characterize chronic liver diseases (CLD). In the earlier stages of CLD, much of the diagnostics involves performing biopsies, which are evaluated by a histopathologist for the presence of e.g. fat, iron, inflammation, and fibrosis. READ MORE

  6. 24. Translational genetics identifies a novel target to treat fatty liver disease

    Author : Kavitha Sasidharan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fatty liver disease; human genetics; GWAS; PSD3; spheroids;

    Abstract : Fatty liver disease (FLD) is rapidly prevailing as the most common liver disease worldwide, with an estimated of one-quarter of the global population affected. Environmental and genetic determinants contribute to FLD susceptibility. READ MORE

  7. 25. Psychopathology in Wilson's Disease

    Author : Kamilla Portala; Birgitta Rembeck; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Wilson´s disease; psychopathology. personality traits; neuropsychological impairment; sleep; CPRS; KSP; Neurovetenskap; Neurology; Neurologi; Psychiatry; psykiatri;

    Abstract : Wilson's disease (WD), bepatolenticular degeneration, is an autosomal recessive disorder caused by mutations in the ATP7B gene, and is characterised by abnormal metabolism and deposition of copper in the liver, brain and other organs. The main aim of this thesis was to investigate the occurrence of psychopathology, as well as personality traits and neuropsychological function in Swedish patients with treated WD. READ MORE