Search for dissertations about: "liver tolerance"

Showing result 1 - 5 of 61 swedish dissertations containing the words liver tolerance.

  2. 1. On the regulation of immune responses to dietary and self antigens

    Author : Susanne Lindgren; Göteborgs universitet; []
    Keywords : Tolerance; regulatory T cells; self antigens; oral tolerance; dietary antigens; intestinal epithelial cells; exosomes; Staphylococcus aureus enterotoxin A;

    Abstract : Regulatory mechanisms are necessary to avoid the misdirected aggressive immune responses responsible for the pathology seen in autoimmunity and allergy. Thymic-derived CD4+CD25+ regulatory T cells are indispensible for this regulation. We investigated if CD4+CD25+ Treg prevents auto-reactive responses in adult peripheral blood and cord blood. READ MORE

  4. 2. Molecular mechanisms behind the liver-induced acceptance of renal grafts in highly sensitized patients

    Author : Madeleine Ingelsten; Göteborgs universitet; []
    Keywords : kidney transplantation; liver tolerance; HLA antibodies; dendritic cells; indoleamine 2; 3-dioxygenase; IL-10; natural killer cells;

    Abstract : Preformed antibodies directed at donor HLA are considered an absolute contraindication for kidney transplantation, because of the high risk of rejection. Thus, patients with high levels of HLA antibodies have little chance of receiving a kidney transplant. READ MORE

  5. 3. Aspects on the Diverse Manifestations of Cystic Fibrosis

    Author : Helga Elidottir; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cystic fibrosis; Glucose tolerance; Diabetes; Liver disease; Continuous glucose monitoring; Oral glucose tolerance test; Lung function; Epidemiolgy; N1303K variant;

    Abstract : .... READ MORE

  6. 4. Immune interactions with the liver

    Author : Azza Karrar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Liver sinusoid; endothelial cells; apoptosis; antibodies; liver immunity; biliary cells; autoimmune liver diseases; estrogen;

    Abstract : The liver has an important role in the induction of immune tolerance and can be a target for immune mediated damage. The following studies are performed to address the role of liver sinusoidal endothelial cells (LSEC) in tolerance induction and to understand some of the mechanisms involved in the pathogenesis of primary sclerosing cholangitis (PSC). READ MORE

  7. 5. Mechanisms of liver allograft rejections

    Author : Xupeng Ge; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Liver transplantation; acute rejection; antibody; biliary epithelial cell; sinusoidal endothelial cell; cholangitis; toll-like receptor;

    Abstract : Liver transplantation (M) has become a standard treatment for many end-stage liver diseases. However, acute rejections still occur in about half of the liver transplant recipients even treated with a combination of different modem immunosuppressants. READ MORE