Search for dissertations about: "locus coeruleus"

Showing result 1 - 5 of 26 swedish dissertations containing the words locus coeruleus.

2. 1. Dopamine neurons in ventral mesencephalon : interactions with glia and locus coeruleus

   Author : Elisabet Berglöf; Ingrid Strömberg; Stephen B. Dunnett; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; ventral mesencephalon; nerve fiber formation; glia; locus coeruleus; grafting; antioxidant-enriched diet; Histology; Histologi;

   Abstract : Parkinson’s disease is a progressive neurodegenerative disorder, characterized by a depletion of the dopaminergic neurons in the substantia nigra. The cause of the disease is yet unknown but age, oxidative stress, and neuroinflammation are some of the features involved in the degeneration. READ MORE

4. 2. Neuropathological findings and staging in dementia

   Author : Hans Brunnström; Tumörmikromiljö; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer disease; concordance; dementia; diagnostics; frontotemporal lobar degeneration; grading; Lewy body disease; locus coeruleus; neuropathology; prevalence; staging; vascular dementia;

   Abstract : Dementia is a clinical syndrome with the development of impairment in multiple cognitive functions (including memory), severe enough to interfere with activities of daily living, as the main symptom. There are a large number of disorders that can lead to dementia, and neuropathological examination after death is necessary to determine the underlying cause with certainty. READ MORE

5. 3. Neuropeptides, 'gaseous' messengers and classic transmitters : electrophysiological and histochemical studies on coexistence and interactions in the nervous system

   Author : Zhi-Qing David Xu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Dorsal root ganglion; galanin; hippocampus; 5-hydroxytryptamine; locus coeruleus; nerve injury; nitric oxide; noradrenaline.;

   Abstract : The distribution and functional role of neuropeptides were studied, with special reference to galanin (GAL) and the free radical nitric oxide (NO). In developing systems GAL expression was observed already at E14 in trigeminal and dorsal root ganglion (DRG) neurons and at E15 in sensory epithelia in ear, eye and nose, as well as at E19 during bone formation. READ MORE

6. 4. Galanin receptor subtypes in rodent models of mood disorders

   Author : Tara Wardi-Le Maitre; Karolinska Institutet; Karolinska Institutet; []
   Keywords : 5-HT1A receptor; galanin; galanin receptor 2 overexpressing mice; locus coeruleus; dorsal raphe; depression-like behavior; forced swim test;

   Abstract : Major depressive disorder (MDD) is a serious mental illness, with a complex etiology. It is a multifactorial disorder caused by a combination of genetic, environmental and epigenetic factors. Exposure to stressful life events seems to be a common, contributing cause of morbidity. READ MORE

7. 5. Short- and long-term cardiovascular and behavioural effects of oxytocin : mechanisms involved and influence of female steroid hormones

   Author : Maria Petersson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : oxytocin; nociceptive thresholds; naloxone; blood pressure; heart rate; spontaneous motor activity; oestrous cycle; ovariectomy; oestradiol; progesterone; weight gain; clonidine; locus coeruleus; alpha 2-adrenoreceptor; cholecystokinin; insulin; gastrin; corticosterone; ACTH; rat;

   Abstract : The aim of the present thesis was to investigate short- and long-term cardiovascular and behavioural effects of oxytocin. In addition, the influence of female steroid hormones as well as possible mechanisms behind the oxytocin induced effects were investigated. READ MORE