Search for dissertations about: "loperamide"

Showing result 1 - 5 of 6 swedish dissertations containing the word loperamide.

  2. 1. Pharmacokinetic and pharmacodynamic analysis of antidiuretic peptides

    Author : Torbjörn Callréus; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lithium; indirect-response model; pharmacodynamics; pharmacokinetics; gastrointestinal absorption; gastrointestinal motility; loperamide; erythromycin; antidiuretic effect; desmopressin; overhydration; vasopressin analogue F992 ; interaction; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : The clinical pharmacology of desmopressin and a new vasopressin analogue (F992) was investigated in healthy human subjects. The common procedure of overhydration of healthy volunteers when studying the antidiuretic effect of a drug, may affect the pharmacokinetics, in particular the volumes of distribution. READ MORE

  4. 2. Advanced Mass Spectrometry Imaging in Neuropharmacology

    Author : Theodosia Vallianatou; Per E. Andrén; Anna Nilsson; Mohammadreza Shariatgorji; Maria Karlgren; Irena Loryan; Nathalie Agar; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mass spectrometry imaging; neuropharmacology; blood brain barrier; drug-drug interactions; aging; tacrine;

    Abstract : Mass spectrometry imaging (MSI) has emerged as a valuable approach for mapping multiple molecular species in sections of diverse tissues. It enables simultaneous detection of numerous compounds (from neurotransmitters to small proteins) in the brain at relatively high lateral resolution (>5 μm) on a routine basis. READ MORE

  5. 3. Collagenous colitis : A study of epidemiology, etiology, clinical features and treatment

    Author : Johan Bohr; Robert Löfberg; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Collagenous colitis (CC) is characterised clinically by chronic watery diarrhoea and histopathologically by an increased submucosal collagen layer. An epidemiologic study of CC during 1984 to 1993 showed a female:male ratio of 9:1. The median age at diagnosis was 64 (28-78) years. The prevalence was 15. READ MORE

  6. 4. Microscopic colitis : studies of epidemiology, clinical features and nitric oxide

    Author : Martin Olesen; Robert Löfberg; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Lymphocytic colitis (LC) and collagenous colitis (CC) arc newly recognised inflammatory bowel diseases belonging to the group of microscopic colitides (MC). They are characterised clinically by chronic non-bloody and watery diarrhoea, and a macroscopically normal or near normal colonic mucosa where diagnostic histopathological abnormalities are found. READ MORE

  7. 5. Pharmacological properties of radiotracers that measure p-glycoprotein function and density

    Author : Pavitra Kannan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Energy-dependent transporters of the ATP-binding cassette (ABC) family regulate the movement of molecules across cellular membranes. Several of these transporters are expressed in the endothelial cells of brain microvessels (blood-brain barrier) to protect brain tissue from exposure to toxins in the blood. READ MORE