Search for dissertations about: "mRNA biogenesis"

Showing result 1 - 5 of 41 swedish dissertations containing the words mRNA biogenesis.

  2. 1. mRNA degradation factors as regulators of the gene expression in Saccharomyces cerevisiae

    Author : Mridula Muppavarapu; Tracy Nissan; Per Sunnerhagen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mRNA decapping; mRNA degradation; Pat1; Edc3; Lsm4; Lsm1-7; P bodies; Dcp2; Transcription; Ribosome biogenesis; Exosome.; molekylärbiologi; Molecular Biology;

    Abstract : Messenger RNA degradation is crucial for the regulation of eukaryotic gene expression. It not only modulates the basal mRNA levels but also functions as a quality control system, thereby controlling the availability of mRNA for protein synthesis. READ MORE

  4. 2. Isolation and functional characterization of Hrp65-binding proteins in Chironomus tentans

    Author : Eva Kiesler; Neus Visa; Benjamin Blencowe; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gene expression; RNA-binding proteins; mRNA biogenesis; nuclear structure; Molecular biology; Molekylärbiologi;

    Abstract : It is well-established that the organization of nuclear components influences gene expression processes, yet little is known about the mechanisms that contribute to the spatial co-ordination of nuclear activities. The salivary gland cells of Chironomus tentans provide a suitable model system for studying gene expression in situ, as they allow for direct visualization of the synthesis, processing and export of a specific protein-coding transcript, the Balbiani ring (BR) pre-mRNA, in a nuclear environment in which chromatin and non-chromatin structures can easily be distinguished. READ MORE

  5. 3. Studies of mRNA transport and localization

    Author : Chandrasekhar Saki Raju; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : During mRNA biogenesis, a subset of newly exported mRNA is assembled into larger RNA granules which are transported to subcellular compartments for localized translation. These mechanisms are critical for asymmetric mRNA and protein distribution and have profound impact on cellular physiology. READ MORE

  6. 4. Training-induced increase in mitochondrial biogenesis

    Author : Emma Hawke; Department of Neurological and Movement Sciences University of Verona; []
    Keywords : alkalosis; acidosis; muscle adaptation; PGC1alpha; cell signalling;

    Abstract : Endurance training leads to an improved ability of muscle to utilize oxygen. This is related to an increased density and function of mitochondria. READ MORE

  7. 5. Biogenesis of messenger and ribosomal RNPs in the eukaryotic cell

    Author : Petra Björk; Juan Valcárcel; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Physical Biology; fysikalisk biologi;

    Abstract : In eukaryotic cells, gene expression involves multi-step processes in the nucleus and the cytoplasm. The different processes engage specific RNA-protein complexes, RNPs. Upon activation of most, if not all genes, a precursor RNA molecule is synthesized that has to be extensively processed and modified. READ MORE