Search for dissertations about: "major histocompability complex"

Found 3 swedish dissertations containing the words major histocompability complex.

2. 1. On genes involved in common neurological disorders : focus on Parkinson's disease

   Author : Caroline Ran; Karolinska Institutet; Karolinska Institutet; []
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   Abstract : Parkinson’s disease and migraine are complex neurological disorders and it is likely that a combination of genetic risk factors are involved in the etiology of both these diseases. Papers in this thesis investigate candidate genes in the search of genetic risk factors contributing to disease. READ MORE

4. 2. The role of the DAMP molecule HMGB1 in neuroinflammation and macrophage activation

   Author : Henna Salo; Karolinska Institutet; Karolinska Institutet; []
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   Abstract : High mobility group box 1 (HMGB1) is a highly conserved nuclear protein expressed in all eukaryotic cells. While its nuclear functions are vital, we know today that HMGB1 also functions as a Damage Associated Molecular Pattern (DAMP). READ MORE

5. 3. Natural killer cell inhibitory and activating receptors : regulatory role in effector functions against normal and tumor cells

   Author : Gustaf Vahlne; Karolinska Institutet; Karolinska Institutet; []
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   Abstract : Natural killer (NK) cells can mediate effector functions as cytokine production and degranulation dependent cytotoxicity against cells that have become aberrant by mutagenesis or by infection. As part of the innate immunity, the NK cells are most important in the direct early defense against infections, and also in indirect shaping of the later adaptive response. READ MORE