Search for dissertations about: "mapk pathogen"
Showing result 1 - 5 of 10 swedish dissertations containing the words mapk pathogen.
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1. Altered cell signaling linked to neurodegeneration : Studies on scrapie-infected neuroblastoma cells and activated microglia
Abstract : Prion diseases are neurodegenerative disorders that can affect humans and animals. The underlying event is a conformational change of the normal cellular prion protein (PrPC) into an aberrant isoform termed PrP-scrapie (PrPSc). PrPSc is thought to lead to neurodegeneration and activation of glial cells. READ MORE
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2. Influence of host genetics on innate immunity and susceptibility to urinary tract infection
Abstract : It has been known for a long time that the clinical manifestations of urinary tract infections (UTI) differ markedly between individuals, ranging from a sometimes beneficial, asymptomatic state to life threatening infections. This variability in clinical manifestation can be explained in part by the arsenal of virulence factors of the bacteria but the predisposition of the patient is equally important. READ MORE
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3. Signalling and activation of TLR4 by Gram-negative bacteria in epithelial cells
Abstract : Lipopolysaccharide (LPS) is a well-characterized pathogen-associated molecule found primarily as a constituent of the outer membrane of Gram-negative bacteria. LPS is known to act on different cell types in a pleiotropic manner. READ MORE
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4. Innate immunity in atherosclerosis : the role of pattern recognition receptors
Abstract : The pathogenesis of atherosclerosis is greatly influenced by the activities of both innate and adaptive immunity. Danger signals such as cholesterol crystals, oxidized LDL, and modified phospholipids may trigger sterile inflammation in atherosclerosis. READ MORE
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5. Tuberculosis - Clinical Value of Initial Host Molecular Signalling and Molecular Fingerprinting
Abstract : Mycobacterium tuberculosis (Mtb) is principally a pulmonary pathogen infecting one-third of the world's population and causing two million deaths annually. The only approved tuberculosis vaccine today is the Mycobacterium bovis bacilli Calmette-Guérin (BCG). READ MORE