Search for dissertations about: "mass spectrometry - LC-MS MS"

Showing result 1 - 5 of 87 swedish dissertations containing the words mass spectrometry - LC-MS MS.

  1. 1. Mass Spectrometry of Biologically Active Small Molecules Focusing on polyphenols, alkaloids and amino acids

    University dissertation from Stockholm : Department of Analytic Chemistry, Stockholm University

    Author : Zdeněk Spáčil; Stockholms universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; LC-MS; LDI; Mass spectrometry; HPLC; UHPLC; polyphenols; phenolic acids; BMAA; NATURAL SCIENCES Chemistry Analytical chemistry Separation methods; NATURVETENSKAP Kemi Analytisk kemi Separationsmetoder; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : The foci of this dissertation are on advanced liquid chromatography (LC) separation and mass spectrometry (MS) techniques for the analysis of small bioactive molecules. In addition to discussing general aspects of such techniques the results from analyses of polyphenols (PPs), alkaloids and amino acids published in five appended studies are presented and discussed. READ MORE

  2. 2. Liquid Chromatography Coupled to Mass Spectrometry Implementation of Chemometric Optimization and Selected Applications

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : My Moberg; Uppsala universitet.; [2006]
    Keywords : Analytical chemistry; liquid chromatography; mass spectrometry; tandem mass spectrometry; electrospray ionization; inductively coupled plasma; chemometrics; optimization; multivariate data analysis; design of experiments; response surface model; siderophore; azathioprine; peptide; Analytisk kemi;

    Abstract : Liquid chromatography (LC) coupled to mass spectrometry (MS) offers highly selective and sensitive analysis of a wide variety of compounds. However, the use of hyphenated experimental set-ups implies that many parameters may have an effect on the studied response. READ MORE

  3. 3. Mass Spectrometry of Non-protein Amino Acids BMAA and Neurodegenerative Diseases

    University dissertation from Stockholm : Department of Environmental Science and Analytical Chemistry, Stockholm University

    Author : Liying Jiang; Stockholms universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neurodegenerative diseases; BMAA; Isomers; LC-MS MS; Cyanobacteria; Diatoms; Seafood contamination; Analytical Chemistry; analytisk kemi;

    Abstract : Neurodegenerative diseases have been shown to correlate positively with an ageing population. The most common neurodegenerative diseases are amyotrophic lateral sclerosis (ALS), Parkinson’s disease and Alzheimer’s disease. READ MORE

  4. 4. Novel Solid Phase Extraction and Mass Spectrometry Approaches to Multicomponent Analyses in Complex Matrices

    University dissertation from Stockholm : Department of Analytical Chemistry, Stockholm University

    Author : Nahid Amini; Stockholms universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Sample preparation; SPE; RAM; GCB µ-trap; GCB disk; High temperature LC; LC MS; ESI; APCI; Matrix effects; LIT-MS; SALDI; Sample screening; Oxidized GCB; Silicon nitride; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; analytisk kemi; Analytical Chemistry;

    Abstract : Analysis of compounds present in complex matrices is always a challenge, which can be partly overcome by applying various sample preparation techniques prior to detection. Ideally, the extraction techniques should be as selective as possible, to minimize the concentration of interfering substances. READ MORE

  5. 5. Mass Spectrometric Applications for Diagnosing Metabolic and Endocrine Diseases

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mark M. Kushnir; Uppsala universitet.; [2008]
    Keywords : Analytical chemistry; biomarker; liquid chromatography; tandem mass spectrometry; LC-MS MS; sample preparation; isomers; steroid hormones; congenital adrenal hyperplasia; polycystic ovary syndrome; Analytisk kemi;

    Abstract : Disease-specific compounds (biomarkers) are analyzed in clinical laboratories to assist with diagnosing diseases. This thesis describes development and validation of liquid chromatography tandem mass spectrometry (LC-MS/MS) based tests for diagnosing a diverse group of endocrine and metabolic diseases. READ MORE