Search for dissertations about: "mass spectrometry - LC-MS MS"

Showing result 21 - 25 of 122 swedish dissertations containing the words mass spectrometry - LC-MS MS.

  2. 21. Statistical and machine learning methods to analyze large-scale mass spectrometry data

    Author : Matthew The; Lukas Käll; Fredrik Levander; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry - LC-MS MS; statistical analysis; data processing and analysis; protein inference; large-scale studies; simulation; Bioteknologi; Biotechnology;

    Abstract : As in many other fields, biology is faced with enormous amounts ofdata that contains valuable information that is yet to be extracted. The field of proteomics, the study of proteins, has the luxury of having large repositories containing data from tandem mass-spectrometry experiments, readily accessible for everyone who is interested. READ MORE

  4. 22. Isocyanates - methodology for gas and particle generation, sampling and detection

    Author : Daniel Gylestam; Marianne Dalene; Gunnar Skarping; Daniel Karlsson; Dhimiter Bello; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Isocyanate; PUR; Dry sampler; PTR-MS; Transfer line; PPE; Environmental Chamber; Respirable Particles; Denuder Impactor; Aerosol; Particles; Impinger; air sampling; LC-MS; di-n-butylamine; DBA; ICA; MIC; HDI; TDI; IPDI; MDI; Occupational Exposure; Exposure; Occupational Health; Analytical Chemistry; analytisk kemi;

    Abstract : Isocyanates are mainly used in the industry for the production of polyurethane (PUR) plastics. Workers are at risk of being exposed during the manufacturing of PUR. During thermal degradation of PUR, isocyanates are released and workers involved in hot work such as fire-fighting, welding etc. may also be exposed. READ MORE

  5. 23. New methods for determination of airborne pollutants : Focus on tetrabromobisphenol A, organophosphate triesters and polycyclic aromatic hydrocarbons

    Author : Johanna Tollbäck; Ulrika Nilsson; Peter Haglund; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Air sampling; sampling methods; indoor air; SPE; SPME; extraction; dynamic extraction; online coupling; SWE; subcritical water extraction; GC MS; LC MS; organophosphate triesters; PAH; tetrabromobisphenol A; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : The work presented in this thesis concerns the development and evaluation of new methods of sampling and analysis of organic pollutants in the indoor and outdoor environment. In Paper I, the development of a new method was reported for the determination of the brominated flame retardant tetrabromobisphenol A (TBBPA) in air using sampling with glass fiber filter and polyurethane foam (PUF), ultrasonic solvent extraction and liquid chromatography coupled to electrospray ionisation mass spectrometry (LC-ESI/MS). READ MORE

  6. 24. Development of analytical methods for the determination of the small molecule component of complex biological systems

    Author : Kristian Pirttilä; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Thomas Moritz; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; metabolomics; data processing; peak characterization; algorithm; multivariate data analysis; chromatography; sequential columns; HILIC; RPLC; liquid chromatography; mass spectrometry; LC; MS; noise-induced hearing loss; NIHL; guinea pig; perilymph; method development; validation; R; C ; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Abstract : The research field of untargeted metabolomics aims to determine the relative abundance of all small metabolites in a biological system in order to find biomarkers or make biological inference with regards to the internal or external stimuli. This is no trivial aim, as the small metabolites are both vast in numbers and extremely diverse in their chemical properties. READ MORE

  7. 25. Analytical method development in liquid chromatography- mass spectrometry based metabolomics

    Author : Ida Erngren; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Gérard Hopfgartner; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Analytical pharmaceutical chemistry; metabolomics; liquid chromatography; mass spectrometry; hydrophilic interaction liquid chromatography; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Abstract : Metabolomics is the analytical field which aims at analyzing all small molecules, metabolites, in a biological system simultaneously. Currently no analytical methods are able to capture the entire metabolome, therefore, the analytical methods are often developed to be as general as possible. READ MORE